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预防性胰管支架置入治疗内镜后胰腺炎临床分析280例 被引量:9

Prophylactic pancreatic duct stenting for post-ERCP pancreatitis
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摘要 目的:研究胰管支架置入在预防内镜后胰腺炎发生中的临床价值.方法:选择2009-12/2012-12于我中心行内镜下逆行胰胆管造影术(endoscopic retrograde cholangio pancreatography,ERCP)术后可能出现胰腺炎而行胰管支架植入术的患者141例(支架组)作为研究对象,与同期未放置胰管支架的139例患者(对照组)进行比较,支架组分别在手术结束时、术后24、48、72、96 h病情平稳后取出胰管支架,术后两组使用相同药物治疗,比较两组术后胰腺炎发生率.结果:支架组ERCP术后胰腺炎(post-ERCP pancreatitis,PEP)发生率2.1%(3/141)低于对照组的10.8%(15/139),支架组无重型胰腺炎发生.结论:预防性胰管支架能降低ERCP患者PEP的发生率,并能减轻PEP的严重程度. AIM: To evaluate the clinical application of pancreatic duct stents in the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. METHODS: From January 2012 to December 2012, we performed pancreatic duct stenting in 141 patients to prevent the occurrence of post-ERCP pancreatitis, and 139 patients who did not undergo pancreatic duct steng in the same period were used as controls. The same medications were given after ERCP in the two groups. The pancreatic duct stents were removed at the end or 24, 48, 72, 96 h after ERCP when the patient's condition was stable. The incidence of post-ERCP pancreatitis was compared between the two groups. RESULTS: The incidence of PEP in the pancreatic duct stenting group was significantly lower than that in the control group (2.1% vs 10.8%, P 〈 0.05). CONCLUSION: Pancreatic duct stenting may, to a certain extent, decrease the incidence of postERCP pancreatitis and reduce its severity.
机构地区 天津市南开医院
出处 《世界华人消化杂志》 CAS 北大核心 2014年第12期1743-1746,共4页 World Chinese Journal of Digestology
关键词 预防性胰管支架 内镜下逆行胰胆管造影术 内镜后胰腺炎 Prophylactic pancreatic duct stenting Endoscopic retrograde cholangiopancreatography Post-ERCP pancreatitis
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