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布地奈德混悬液喷喉对于喉罩拔除后咽痛的疗效观察 被引量:6

Effect of budesonide suspension spray to the throat sore after the removal of the laryngeal mask
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摘要 目的:探讨布地奈德混悬液喷喉对于喉罩拔除后咽痛的疗效。方法:将90例使用喉罩的妇科和乳腺外科手术的患者,随机分为布地奈德组(A组,n=30)、生理盐水组(B组,n=30)和利多卡因组(C组,n=30)。患者完全清醒拔除喉罩后A组给予布地奈德混悬液1 ml(内含布地奈德0.5 mg)+生理盐水1 ml喷喉,B组给予生理盐水2 ml喷喉,C组给予2%利多卡因2 ml喷喉。分别记录喉罩置入的次数,喉罩置入至拔除时间,喉罩拔除后1 h(T1)、4 h(T2)、12 h(T3)、24 h(T4)的咽喉痛情况和严重程度。结果:3组患者年龄、体重、喉罩置入次数、喉罩置入至拔除时间差异无统计学意义(P>0.05)。A组与B、C两组相比在T1、T2、T3时间点疼痛分级的差异有统计学意义(P<0.05)。结论:布地奈德混悬液喷喉对于喉罩拔除后的患者可有效降低术后24 h内咽痛发生率,同时明显减轻咽痛程度。 Objective:To observe the effect of budesonide suspension spray to the throat sore after the removal of the laryngeal mask .Methods:Ninety patients scheduled for gynecological and mammary surgery with the laryngeal mask airway management , were randomly assigned into three groups: the budesonide group ( group A, n=30 ) , which received 1 ml budesonide suspension ( containing 0 .5 mg budesonide ) and 1 ml physiological saline spray;saline group ( group B, n =30 ) , which were given 2 ml physiological saline throat spray; and lidocaine group (group C, n=30), which were administered with 2 ml 2% lidocaine spray.All the spray was given after the removal of laryngeal mask when the patients were fully awake .The number of attempts required until successful laryngeal mask insertion , the time course from LMA insertion to removal , and the severity of throat sore at 1 h ( T1) , 4 h ( T2 ) , 12 h ( T3 ) and 24 h ( T4 ) after the removal of LMA were obtained .Results: There's no significance of age , weight , the number of attempts required until successful laryngeal mask insertion and the time course from LMA insertion to removal among the three groups statistically ( P〉0 .05 ) .Significantly decrease of throat sore in group A was observed at T 1, T2 and T3 compared to goup B and C ( P〈0.05) .Conclusion: The incidence and severity of throat sore after removal of LMA were significantly decreased with the administration of budesonide throat spray within 24 hours postoperatively .
出处 《东南大学学报(医学版)》 CAS 2014年第3期332-334,共3页 Journal of Southeast University(Medical Science Edition)
关键词 布地奈德混悬液 喷喉 喉罩 咽痛 budesonide suspension spay laryngeal mask airway throat sore
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