期刊文献+

GDF-15血浆水平及其基因多态性与不稳定型心绞痛

下载PDF
导出
摘要 1研究背景 生长分化因子-15(growth and differentia tion factor-15)GDF-15是转化生长因子-β超家族(TGF-β)的成员之一,研究表明GDF-15血浆水平与心血管疾病的发生和发展密切相关,其在心肌缺血及缺血再灌注损伤等情况下迅速表达增高,在不稳定型心绞痛进展中起保护作用。近些年来的研究逐渐指向GDF-15基因多态性与心血管疾病的相关性,是一个新的研究领域[3]。本文对GDF-15基因多态性及血浆水平与不稳定型心绞痛的研究进展综述如下。
出处 《医学检验与临床》 2014年第2期57-59,共3页 Medical Laboratory Science and Clinics
  • 相关文献

参考文献12

  • 1Ago T, Sadoshima J. GDF15, a cardioprotective TGF- beta superfamily protein. CircR.es, 2006, 98(3) : 342-- 350. 被引量:1
  • 2Kempf T, Eden M, Strelau J, etal.The transforming growth factor -beta superfamilymember growth- differentiation factor - 15 protects the heart fromischemia / reperfusion injury. Circ Res, 2006, 98:351 -- 360. 被引量:1
  • 3花苏榕,张抒扬.生长分化因子-15基因多态性的研究进展[J].中华临床医师杂志(电子版),2011,5(22):6688-6690. 被引量:3
  • 4Bottner M, LaaffM,Schechinger B, et al Characterization of the rat mouse, and human genes of growth/differentiation factor-15/macrophage inhibiting cytokine-1 (GDF-15/ MIC-1 ) [J].Gene, 1999.237 : 105-111. 被引量:1
  • 5Kempf T, Hom-Wichmann R, Brabant Get al Circulating concentrations of growth--differentiation factor -15 in apparently healthy elderly individuals and patients with chronic heart failure as assessed by a new immunoradiometric sandwich assay.Clin Chem, 2007, 53(2) : 284--291. 被引量:1
  • 6wollert KC.Growth-differentiation factor-1 5 in cardiovascular disease : from bench to bedside, and back. Basic Res Cardiol, 2007, 102(5) : 412-415. 被引量:1
  • 7吴俊红,宋世雄.生长分化因子15与不稳定性心绞痛冠状动脉狭窄的相关性[J].海南医学院学报,2011,17(5):607-609. 被引量:2
  • 8邓明尧,吴国平,冯旭霞,罗江宾.不稳定性心绞痛患者血清生长分化因子15与TIMI危险评分的相关性[J].南方医科大学学报,2011,31(7):1277-1278. 被引量:11
  • 9WangX,YangX,SunK,,etal.Thehaplotype of the Growth- differentiation factor 15 gene is associated with left ventricular hyperophy in humannessential hypertension. Clinsci(lond),2010,118:137.145. 被引量:1
  • 10ChenZ,XieF,MaG,etal.Study of the association factor 15 gene polymorphism and coronary artery disease in a chinese population.MolBiol Rep,2011,38:5085-5091. 被引量:1

二级参考文献38

  • 1梁瀛,牛杰,高炜.生长分化因子-15的心血管作用[J].心血管病学进展,2009,30(6):934-938. 被引量:4
  • 2Ago T, Sadoshima J. GDF15, a cardiop rotective TGF-beta superfamily protein[J]. Circ Res,2006, (98) : 294- 297. 被引量:1
  • 3Gensini GG. A more meaningful scoring system for determining the severity of coronary heart disease [J].Am J Cardiol, 1983,51(5) : 606. 被引量:1
  • 4Kempf T, Eden M, Strelau J, et al. The transforming growth factor-beta superfamily member growth-differentiation factor-15 protects the heart from ischem ia/reperfusion injury[J]. Circ Res, 2006,98: 351-360. 被引量:1
  • 5Brown DA,Breit S N,Buring J, et al. Concentration in plasma of macrophage inhibitory cytokine - 1 and risk of cardiovascular events in women:a nested case - controlstudy[J]. Lancet, 2002, 359: 2159-2163. 被引量:1
  • 6Ago T, Sadoshima J. GDF15, a cardiop rotective TGF-beta superfamily protein[J]. Circ Res, 2006(98): 294-7. 被引量:1
  • 7中华医学会心血管疾病学分会.不稳定性心绞痛诊断和治疗建议.中国循环杂志,2001,:226-226. 被引量:1
  • 8Kempf T, Eden M, Strelau J, et al. The transforming growth factor-beta superfamily member growth-differentiation factor-15 protects the heart from ischemia/reperfusion injury [J]. Circ Res, 2006, 98(3): 351-60. 被引量:1
  • 9Khan SQ, Ng K, Dhillon O, et al. Growth differentiation factor-15 as a prognostic marker in patients with acute myocardial infarction [J]. Eur Heart J, 2009, 30(9): 1057-65. 被引量:1
  • 10华宁,唐发宽,钮炜西,方智,陆宏.不稳定型心绞痛患者TIMI危险评分与冠状动脉病变严重程度相关[J].心脏杂志,2007,19(4):445-447. 被引量:3

共引文献12

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部