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小脑半球髓母细胞瘤与星形细胞瘤的MRI对比研究 被引量:5

Comparative study between cerebellar hemispheric medulloblastoma and astrocytoma on MRI
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摘要 目的:比较小脑半球髓母细胞瘤与星形细胞瘤在常规MRI上的影像表现,以提高诊断水平。方法:回顾性分析21例小脑半球髓母细胞瘤和31例星形细胞瘤在平扫和增强MRI上的表现,分别比较儿童组和成人组两者在发病年龄、性别、肿瘤大小、信号、瘤周水肿、强化程度、强化形态、是否靠近脑表面等方面的差异。结果:无论儿童组还是成人组,髓母细胞瘤呈斑片状强化的例数要多于星形细胞瘤,差异具有显著性意义(P<0.01)。儿童组中,髓母细胞瘤呈实内小囊型,靠近脑表面,存在血管流空影及呈无或轻度强化的例数均多于星形细胞瘤,二者差异有统计学意义(P值均<0.05);成人组中,髓母细胞瘤呈实内小囊型,靠近脑表面的例数多于星形细胞瘤,差异具有统计学意义(P值均<0.05)。小脑半球髓母细胞瘤与星形细胞瘤在其他方面的差异无统计学意义。结论:与星形细胞瘤相比,小脑半球髓母细胞瘤多表现为靠近小脑表面的实性病灶,内多发小囊,增强后呈斑片状强化。若这些征象发生在儿童,另观察到血管流空影,增强后呈无或轻度强化,我们应更倾向于髓母细胞瘤的诊断。 Objective: To compare the findings between cerebellar hemispheric medulloblastoma and astrocytoma on routine MRI and to improve the diagnostic level. Methods: The MRI findings of 21 cases of medulloblastoma and 31 cases of astrocytoma in the cerebellar hemisphere were retrospectively analyzed, patients' age and sex, tumor size, signal, peritumoral edema, the degree and morphology of enhancement, tumor close to the surface of cerebellar or not were compared in children group and adult group. Results: Both in children and in adults, the number of medulloblastoma cases with patchy enhance- ment occurred more often than that in astrocytoma, there was significant difference between the.tw0 kinds of tumors (P〈0.01). In children group, there were more cases of medulloblastoma closed to brain surfacel with flow void, small intratumoral cysts, mild or no enhancement were more than those in astrocytoma. There was statistic difference between them (P〈0.05). In adult group, the number of medulloblastoma cases close to brain surface, small intratumoral cysts were more than that in astrocy- toma. The difference was statistically significant(P〈0.05). Cerebellar hemispheric medulloblastoma and astrocytoma were not dif- ferent in other aspects. Conclusion: Compared with astrocytoma, medulloblastoma in the cerebellar hemisphere showed a ten- dency toward being close to the surface of cerebellar, solid mass with small cyst and patchy enhancement. Also, if these signs associated with flow void, slight or no enhancement after contrast observed in children, we are more inclined to make a diagnosis of medulloblastoma.
作者 贾思 孙波
出处 《中国临床医学影像杂志》 CAS 2014年第5期305-308,共4页 Journal of China Clinic Medical Imaging
关键词 小脑肿瘤 髓母细胞瘤 星形细胞瘤 磁共振成像 Cerebellar neoplasms Medulloblastoma Astrocytoma Magnetic resonance imaging
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