摘要
目的比较桂皮醛、薄荷醇、茴香醛、丁香酚4种中药单体牙根尖周炎常见厌氧菌的抑菌效果。方法琼脂法测定4种中药单体对牙根尖周炎常见厌氧菌的抑菌活性,评价4种中药单体制备的氧化锌根充糊剂对建立体外根管感染模型的抗菌作用。结果 4种中药单体对4种常见菌均具有抑菌活性。桂皮醛对牙卟啉单胞菌、微小消化链球菌和具核梭杆菌的抑制活性优于薄荷醇、茴香醛、丁香酚(P<0.05);丁香酚对粪肠球菌的抑菌活性高于薄荷醇、桂皮醛和茴香醛组(P<0.05)。与琼脂法测定的抗菌活性一致。结论桂皮醛抗菌活性优于薄荷醇、茴香醛,可以替代丁香酚应用于根管治疗。
Objective To investigate the antimicrobial effect of four kinds of traditional Chinese medicine monomer on common anoxybiontic in periapicalitis .Methods Antimicrobial effect in v itro of four kinds of tradi-tional Chinese medicine monomer on common anaerobic bacteria in periapicalitis was determined by agar plate method .Then ,we evaluated antimicrobial effect of filling root by preparation four kinds of traditional Chinese medicine monomer of zinc oxide paste using the method of establishing root canal infection mode combined with agar plate method .Results Four kinds of traditional Chinese medicine monomer have antibacterial activity against four common bacteria in periapicalitis .Bacteriostatic activity of cinnamic aldehyde against P .gingivalis , Pep-tostreptococcus micros and Fusobacteriumnucleatum is superior to the menthol ,anise aldehyde and eugenol （ P＆lt;0 .05）;Bacteriostatic activity of eugenol on Enterococcus faecalis is higher than the menthol ,cinnamic aldehyde and fennel aldehyde group （ P＆lt;0 .05） .Results of antimicrobial activity are consistent with those of the agar plate method .Conclusion Antibacterial activity of cinnamic aldehyde is better than that of menthol ,anise aldehyde , which can replace eugenol used in root canal therapy.
出处
《山西医药杂志》
CAS
2014年第10期1108-1110,共3页
Shanxi Medical Journal
基金
军队十二五课题资助项目(CWS11G038)
关键词
根尖周炎
丁香酚
桂皮醛
Periapical periodontitis
Eugenol
Cinnamaldehyde
