摘要
目的:分析归脾汤加减联合地西泮对心脾两虚型失眠症患者睡眠质量的影响。方法:采用随机数字表法将111例确诊心脾两虚型失眠症患者分为两组,对照组给予地西泮治疗,观察组给予归脾汤加减联合地西泮治疗,均治疗30d后对比睡眠质量指数评分和药物安全性。结果:观察组总有效率92.86%明显高于对照组80.00%,P<0.05;观察组匹茨堡睡眠质量指数平均评分(6.51±1.24)分明显低于对照组(8.35±1.31)分,P<0.01;观察组不良反应发生率1.89%(1/56)明显低于对照组14.55%(8/55),P<0.05。结论:归脾汤加减联合地西泮对心脾两虚型失眠症患者效果确切,能够有效改善睡眠质量和降低西药不良反应,值得临床对中药作用机制继续研究和探讨。
Objective：To analyze the sleeping quality in insomnia patients treated with Guipi decoction plus diazepam. Methods：111 patients were randomly divided into two groups by number table. The control group was given diazepam, the observe group was given Guipi decoction more. The index score of sleeping quality and medicine security in two groups were recorded and compared. Results：The total efficacy in the observation was 92.86%, which is better than 80.00% in the control, P〈0.05. The score of average rate in sleeping quality （6.51±1.24） was obviously lower than that in the control （8.35±1.31）, P〈0.01; the incidence of adverse reactions was 1.89%（1/56）, which is lower than that in the control group （8/55）, P〈0.05. Conclusion：Guipi decoction plus diazepam has obvious effects, can improve the sleeping quality and reduce adverse reactions, was worthy of further discussion.
出处
《中医临床研究》
2014年第10期31-32,共2页
Clinical Journal Of Chinese Medicine
关键词
归脾汤
地西泮
心脾两虚型
失眠
睡眠质量指数
药物安全性
Guipi decoction
Diazepam
Heart and spleen deficiency type
Insomniacs
Index of sleeping quality
Medicine security
