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ALK阴性间变性大细胞淋巴瘤的研究进展

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摘要 ALK阴性间变性大细胞淋巴瘤(Anaplastic large cell lymphoma,ALK-ALCL)是一种罕见的T细胞淋巴瘤。它CD30表达阳性,而间变性淋巴瘤激酶(anaplastic lymphoma kinase,ALK)表达阴性。在2008WHO淋巴瘤分类中ALK-ALCL是一个暂定的疾病类型[1],目前,学者们还没找到它的明确病因,且其进展较迅速,总体预后较差。鉴于此,需要对它进一步深入的研究,进而及时诊断与治疗此病,改良预后。本文从形态学,遗传学,免疫表型,临床特征及治疗等方面对该疾病的研究进展进行综述。
作者 周碧霞 邓飞
出处 《药物与人》 2014年第4期22-24,共3页 Medicine & People
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