摘要
以气动挤出沉积多孔生物骨支架成型机作为成型设备,以海藻酸钠(SA)与羟基磷灰石(HAP)作为成型材料,制造出了最适宜骨组织细胞生长的孔隙率和良好的内部连通结构的人工牙槽骨模型,优选了在快速成型过程中对牙槽骨质量的影响因素,并测试了在不同海藻酸钠浓度成型、不同烧结温度后处理情况下人工牙槽骨的力学性能。结果表明:当海藻酸钠浓度为5%,与羟基磷灰石的配比为1∶1.1时获得了良好的宏观外形与较优的微观孔隙结构,找到了羟基磷灰石形成骨陶瓷的最佳温度为1 200℃。
By the pneumatic extrusion deposition porous bone scaffold rapid prototyping machine as molding equipment,with So-dium alginate （SA） and hydroxyapatite （HAP） as the molding materials,the most suitable for bone tissue cell growth porosity and perfect communication with the interior structure of the artificial alveolar model was produced. The alveolar bone quality impact factors in the process of rapid prototyping were optimized in selection,and the artificial alveolar bone mechanical properties of molding in the type of alginate concentration,different calcining temperature post-processing case was tested. The results show that a good shape and optimum macro microscopic pore structure is gotten when the alginate concentration of 5% and the hydroxyapatite ratio of 1∶1.1,and the best temperature ceramic hydroxyapatite bone formation is 1 200 ℃.
出处
《机床与液压》
北大核心
2014年第9期84-86,共3页
Machine Tool & Hydraulics
基金
国家自然科学基金项目(81060088)
关键词
气动挤出沉积成型
组织工程
牙槽骨
羟基磷灰石
Pneumatic precision extrusion deposition modeling
Tissue engineering
Alveolar bone
Hydroxyapatite
