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神经毒性自评量表的信度及效度评估 被引量:6

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摘要 目的探讨中文版患者神经毒性自评(PNQ)量表在评价化疗药物草酸铂周围神经毒性中的信度和效度。方法采用中文版PNQ和医师评估量表(NCI—CTC),分别对接受草酸铂化疗的105例结直肠癌患者进行问卷调查和医师评估;分析PNQ量表的信度、效度及与NCI—CTC量表条目的相关性。结果PNQ量表具有良好的重测信度(相关系数为0.512~0.650,P〈0.01)和良好的内部一致性(Crocnbachot系数为0.82);PNQ量表各条目与总分的相关系数为0.524—0.609(P〈0.01),PNQ量表各条目与NCI—CTC量表各条目的相关系数为0.435~0.568,(P〈0.05或P〈0.01),具有良好内容效度和效标效度;因子分析结果示PNQ量表存在2个公因子,累积方差贡献率为86.474%。结论中文版PNQ量表具有良好信度和效度,叮用于临床评估化疗药物草酸铂周围神经毒性。
出处 《中华物理医学与康复杂志》 CAS CSCD 北大核心 2014年第5期388-390,共3页 Chinese Journal of Physical Medicine and Rehabilitation
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