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去铁敏对心肌的保护作用

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摘要 去铁敏(Desferrioxamine mesylate,DFO)是从链球菌中提取的一种铁载体,为高选择性的铁螯合剂。它对Fe2+亲和力较低,对Fe3+的亲和力极高(Kd=1031),是铜亲和常数的107倍,而对钙的亲和力可忽略不计(Kd=102),还可与镓、铝等金属离子结合。去铁敏主要与Fe3+以l:l比例结合形成铁胺复合物,
出处 《西南军医》 2014年第3期311-313,共3页 Journal of Military Surgeon in Southwest China
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