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腹腔镜下子宫动脉阻断术联合子宫肌瘤剔除术对患者卵巢功能的影响 被引量:22

Influence of Laparoscopic Uterine Artery Occlusion Combined Myomectomy on Ovarian Function
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摘要 目的研究腹腔镜下子宫动脉阻断术联合子宫肌瘤剔除术对患者卵巢功能的影响.方法选择自2011年1至2013年1月妇产科收治的子宫肌瘤患者92例,随机分为对照组和观察组,分别接受腹腔镜下子宫肌瘤剔除及子宫动脉阻断术联合子宫肌瘤剔除术,分别有44例、48例.对2组患者的性激素及AMH及窦卵泡数、卵巢早衰症状进行评估.结果观察组及对照组术后FSH、LH、E2较本组术前虽略有变化但差异无统计学意义(P>0.05),观察组术后较对照组术后FSH、LH虽略有升高但差异无统计学意义(P>0.05),观察组术后较对照组术后E2虽略有升高但差异无统计学意义(P>0.05).观察组及对照组术后AMH、窦卵泡数较本组术前虽略有变化但差异无统计学意义(P>0.05),观察组术后较对照组术后AMH及窦卵泡数虽略有下降但差异无统计学意义(P>0.05).观察组及对照组治疗后阴道干涩发生率均有增高但差异无统计学意义(P>0.05).结论腹腔镜下子宫动脉阻断术联合子宫肌瘤剔除术对患者卵巢功能虽略有影响,但不会导致性激素水平及卵巢储备功能的显著下降. Objective The purpose of this study was to investigate the influence of laparoscopic uterine artery occlusion combined myomectomy on ovarian function in patients.Methods Ninety-two patients with uterine fibroids from January 2011 to January 2013 were randomly divided into control group (44 cases) and observation group (48 cases).Sex hormones,AMH and antral follicle count,and the symptoms of premature ovarian failure were evaluated.Results FSH,LH,E2,AMH,and antral follicle count showed no significant differences in observation and control groups before and after surgery (P > 0.05).Compared with control group,FSH,LH,E2,AMH,and antral follicle count increased slightly after operation,but there were no significant differences (P >0.05).The incidence of vaginal dryness increased in the observation and control groups after treatment but with no significant difference (P > 0.05) Conclusion Laparoscopic uterine artery occlusion combined myomectomy surgery showed a slight impact on ovarian function,but it does not cause significant declines in sex hormone levels and ovarian reserve function.
作者 何红霞 段钊
出处 《昆明医科大学学报》 CAS 2014年第5期81-84,共4页 Journal of Kunming Medical University
基金 陕西省自然科学基金资助项目(2013JM4012)
关键词 子宫肌瘤 子宫动脉阻断 子宫肌瘤剔除术 卵巢功能 Uterine fibroids Uterine artery occlusion Myomectomy Ovarian function
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