摘要
目的了解泌尿系感染病原菌的菌群分布于耐药特点,为临床选用抗菌药物提供依据。方法通过细菌分离鉴定和药敏试验方法,对976例泌尿系感染者病原学标本进行了检测与分析。结果引起泌尿系感染的病原菌种类主要包括大肠埃希菌、肺炎克雷伯菌、变形杆菌、肠球菌、铜绿假单胞菌和真菌。大肠埃希菌和肺炎克雷伯菌等两株优势菌中,产ESBLs菌株分别占62.2%和28.1%。泌尿系感染的病原菌仅对亚胺培南保持较高的敏感性,对第3代头孢菌素、磺胺类、喹若酮类和氨基糖甙类抗菌药物耐药性均比较高。结论泌尿系感染的病原菌主要是大肠埃希菌等革兰阴性杆菌,对临床常用抗菌药物普遍耐药。
Objective To understand the bacterial distribution and the antibiotic resistance of urinary tract infections, and to provide instructions for the clinical application of antibiotics. Methods Identification and drug sensitivity test were used to detect and analyze pathogenic bacteria isolated from clinical specimen from 976 urinary tract infections patients. Results The main pathogenic bacteria species causing urinary tract infection included Escherichia coli, Klebsiella pneumo- nia, Bacillus proteus, Enterococcus, Pseudomonas aeruginosa and fungi. ESBLs producing strains accounted for 62. 2% and 28. 1% respectively in two dominate bacteria species Escherichia coli and KlebsieUa pneumonia. It was found that these uri- nary tract infections related bacteria only still kept sensitivity to Imipenem, but had developed relatively high resistance to the third generation antibiotic Cephalosporins, Sulfonamides, Quinoloines and Aminoglycoside. Conclusion The major part of the urinary tract infection in clinic is caused by Gram - negative bacteria especially Escherichia coli, and theses bac- teria have developed extensive resistance to commonly used antibiotics regents in clinic.
出处
《中国消毒学杂志》
CAS
北大核心
2014年第4期375-376,379,共3页
Chinese Journal of Disinfection
关键词
泌尿系感染
病原菌
抗菌药物
耐药性
urinary tract infection
pathogenic bacteria
antibiotic regents
drug resistance
