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急性心肌梗死患者2年随访分析 被引量:6

2-year follow-up study in patients with acute myocardial infarction
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摘要 目的探讨急性心肌梗死(AMI)患者的住院死亡、1年死亡和2年死亡情况,分析与死亡率相关的危险因素。方法入选我院2007--2010年AMI住院患者,通过病例查询统计住院死亡率,通过电话联系和查询医院信息系统进行随访,统计其1年和2年死亡率。并分析与AMI患者住院死亡、1年死亡和2年死亡率相关的危险因素。结果共纳入424例AMI患者,其住院死亡、1年死亡和2年死亡率分别为4.2%、14.4%和17.5%。多元回归分析显示,心力衰竭史、左心室射血分数(LVEF)与AMI患者住院死亡、1年死亡和2年死亡相关[心力衰竭史:OR(95%a)分别为7.66(2.35—25.00)、5.94(3.32~15.21)和4.83(1.94~12.01);LVEF:OR(95%CI)分另1为0.93(0.88~0.98)、0.97(0.23—0.99)和0.96(0.94~0.98)];年龄与AMI患者1年死亡和2年死亡有关,OR(95%CI)分别为1.15(1.10~1.22)和1.14(1.10~1.20)。合并疾病中,与AMI患者住院死亡率相关的危险因素包括呼吸衰竭、消化道出血[0R(95%C1)分别为5.11(1.28~20.45)、6.83(1.65。28.22)]。与AMI患者1年死亡率相关的危险因素有脑卒中、肺炎、呼吸衰竭、消化道出血和肿瘤[0尺(95%CI)分另1为4.35(1.30~14.53)、6.92(2.69—17.80)、4.17(1.45—14.99)、4.74(1.37~16.41)和6.14(1.52~24.79)]。与AMI患者2年死亡率相关的危险因素有肺炎、呼吸衰竭、消化道出血、肿瘤、肾功能不全[OR(95%CI)分别为4.39(1.71~11.11)、4.22(1.48,12.06)、4.93(1.39~17.45)、10.62(2.72—41.54)和1.63(1.03~2.56)]。结论心力衰竭史和年龄可能是AMI患者住院死亡、1年死亡和2年死亡率的独立危险因素。肺炎、呼吸衰竭、消化道出血、肿瘤、肾功能不全等合并症可能会进一步增加AMI Objective To investigate the in-hospital, 1-year and 2-year mortalities in patients with acute myocardial infarction (AMI) and the associated risk factors. Methods The 424 AMI patients were selected finally during 2007 to 2010 in our hospital. In-hospital, 1-year and 2-year mortalities were obtained by means of ease inquiry, phone call and Hospital Information System (HIS). Results The in-hospital, 1- year and 2-year mortalities were 4. 2% , 14. 4% and 17.5% , respectively. The management of AMI patients became more standardized on the basis of guidelines. Logistic regression analysis showed that heart failure history and left ventricular ejection fraction (LVEF) was related to in-hospital, 1-year and 2-year mortalities of AM I. The OR (95 % CI) of heart failure history were 7.66 (2. 35 - 25.00) , 5.94 (3.32 - 15.21 ) and 4. 83 ( 1.94 - 12. O1 ), respectively. The OR ( 95 % C1) of LVEF were 0. 93 ~ O. 88 - 0. 98), 0. 97 ( 0. 23 - 0. 99) and 0. 96 (0. 94 - 0. 98 ), respectively. Age was related to 1-year and 2-year mortalities. The OR (95% CI) were 1.15(1.10 - 1.22) and 1.14(1.10 - 1.20). In regard to concomitant diseases, respiratory failure and gastrointestinal bleeding were related to in-hospital mortality of AMI, and the OR (95% CI) were 5. 11 ( 1.28 - 20.45 ) and 6. 83 ( 1.65 - 28. 22). Stroke, pneumonia, respiratory failure, gastrointestinal bleeding and tumor were related to 1-year mortality of AMI, with the 0R(95% CI) were 4. 35(1.30-14.53), 6.92(2.69-17.80), 4.17(1.45-14.99), 4.74(l. 37-16.41) and 6.14(1.52- 24. 79 ) , respectively. Pneumonia, respiratory failure, gastrointestinal bleeding, tumor and renal dysfunction were related to 2-year mortality of AMI, with the OR ( 95 % CI) were 4. 39 ( 1.71 - 11.11 ), 4. 22 ( 1.48 - 12. 06), 4. 93 ( 1.39 - 17.45 ), 10. 62 (2.72 - 41.54) and I. 63 ( 1.03 - 2. 56), respectively. Conclusions Heart failure history and age may be the independent risk factor
出处 《中国心血管杂志》 2014年第2期81-85,共5页 Chinese Journal of Cardiovascular Medicine
关键词 急性心肌梗死 死亡率 危险因素 合并症 Acute myocardial infarction Mortality Risk factors Concomitant diseases
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