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DPP-4抑制剂的有效性和安全性评价 被引量:3

Efficacy and Safety of Dipeptidyl peptidase-4 inhibitors
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摘要 二肽基肽酶4(DPP-4)抑制剂是一类基于肠促胰素的新型的口服降糖药物,其出现为2型糖尿病患者带来新的选择,目前我国已有5种DPP-4抑制剂被SFDA批准上市。多项研究表明其无论单药还是与其他药物联合使用均能降低HbA1c、空腹血糖及餐后血糖,并具有较低低血糖风险,对体重的影响中性,不影响胃排空等特点。具有较高的有效性及良好的安全性和耐受性。但是长期用药的有效性和安全性仍缺乏足够证据。
出处 《药品评价》 CAS 2014年第7期36-43,共8页 Drug Evaluation
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  • 1Yuichi Kojima,Hideyoshi Kaga,Shinu Hayashi,Toru Kitazawa,Yuko Iimura,Makoto Ohno,Michiyasu Yoshitsugu,Mutsunori Fujiwara,Toru Hiyoshi.Comparison between sitagliptin and nateglinide on postprandial lipid levels: The STANDARD study[J].World Journal of Diabetes,2013,4(1):8-13. 被引量:5
  • 2PARK H, PARK C, KIM Y, et al. Efficacy and safety of dipep- tidyl peptidase-4 inhibitors in type 2 diabetes : meta-analysis [ J ]. Ann Pharmacother, 2012, 46 ( 11 ) : 1453 - 1469. 被引量:1
  • 3AHRIN B. Emerging dipeptidyl peptidase-4 inhibitors for the treatment of diabetes[ J]. Expert Opin Emerg Drugs, 2008, 13 (4) :593 -607. 被引量:1
  • 4KARAGIANNIS T, PASCHOS P, PALETAS K, et al. Dipepti- dyl peptidase-4 inhibitors for treatment of type 2 diabetes mellitus in the clinical setting: systematic review and meta-analysis[ J]. BMJ, 2012, 344: e1369. 被引量:1
  • 5MOHAN V, YANG W, SON HY, et al. Efficacy and safety of sitagliptin in the treatment of patients with type 2 diabetes in Chi- na, India, and Korea[J]. Diabetes Res Clin Pract, 2009, 83 (1):106-116. 被引量:1
  • 6Meigs JB. Epidemiology of cardiovascular complications in type 2 diabetes mellitus[J]. Acta Diabetol, 2003, 40(Suppl 2): $358-$361. 被引量:1
  • 7National diabetes fact sheet: general information and national estimates on diabetes in the United States, 2007. Atlanta: Centers for Disease Control and Prevention, 2008 (http://www. cdc. gov/diabetes/pubs/pdf/ndfs_2007, pdf). 被引量:1
  • 8Guidance for industry: diabetes mellitus-evaluating cardiovascular risk in new antidiabetic therapies to treat type 2 diabetes. Silver Spring, MD: Food and Drug Administration, December 2008 (www. fda. gov/downloads/ Drugs/Guidance Compliance Regulatory Information/ Guidances/ ucm071627, pdf). 被引量:1
  • 9Jose T, lnzucchi SE. Cardiovascular effects of the DPP-4 inhibitors[J]. Diab Vasc Dis Res, 2012, 9: 109-116. 被引量:1
  • 10Mannucci E, Dicembrini I. Incretin-based therapies and cardiovascular risk[J]. Curr Med Res Opin, 2012, 28(5): 715-721. 被引量:1

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