促炎细胞因子在自发性早产中的研究进展被引量：6

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摘要自发性早产是常见的妊娠期并发症之一,感染和胎膜早破是其主要原因。促炎细胞因子白细胞介素(interleukin,IL)-1、-6、-8和肿瘤坏死因子(tumor necrosis factor,TNF)-α等参与妊娠全过程,动物实验、体外实验和临床试验证实促炎细胞因子与自发性早产的发生相关。羊水,孕妇外周血及宫颈阴道液中IL-6,IL-8,TNF-α可作为预测早产发生的指标,对促炎因子的更深入研究可为早产防治提供新的依据。

作者丁晓颖倪鑫古航

机构地区上海市浦东新区妇幼保健院妇产科第二军医大学生理教研室第二军医大学附属长海医院妇产科

出处《中国优生与遗传杂志》 2014年第4期134-136,共3页 Chinese Journal of Birth Health & Heredity

基金上海市国际科技合作基金项目(13430722900)

关键词促炎细胞因子自发性早产预测

分类号 R714.21 [医药卫生—妇产科学]

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1Chandirumani M, Seed PT, Orsi NM,et al. Limited relationship be- tween cervico -vaginal fluid cytokine profiles and cervical shortening in women at high of spontaneous preterm birth [ J ]. PloS 0ne,2012,7 (12): e52412. 被引量：1
2Uchide N, Ohyama K, Bessho T,et al. Possible rulos of proinflamnmto- ry and chemoattractive cytokines produced by human fetal membrane cells in the pathology of adverse pregnancy outcomes associated with influenza virus infection [J].diators Inflamm, 2012, 2012: 270670. 被引量：1
3Terzidou V. Preterm labour biochemical and endocrinological prepara- tion for parturition[J]. Best Pract Res Clin Obstet Gynaecol,2007,21 (5) : 729 - 756. 被引量：1
4Saito S,Nakashima A,Shima T,et al. Thl/Th2/Thl7 and regulatory T- cell paradigm In pregnancy[ J ]. Am J Repred Immunol, 2010,63 (6):601 -610. 被引量：1
5Lyon D,Cheng CY ,Hewland L, et al. Integrated review of cytokines in mammal,cord and newborn blood: Part I -associations with ple. term birth[J]. Bid Res Num,2010,11(4):371 -376. 被引量：1
6Castro - Leyva V, Espejel - Nunez A, Barcoso G, et al. preserved ex vivo inflammatory status in decidual cells from women with preterm la- bcr and subclinical intrau - terine infection [ J ]. PIoS One, 2012,7 (8) : e43605. 被引量：1
7Saini R, Saini S, Saini SR. Periodontitis: A risk for delivery of prema- ture labor and low birth weight infants[J]. J Nat Sci Bid Med,2011, 2(1):50 -52. 被引量：1
8Kumar D ,Schatz F,More RM,et al. The effects of thrembin and cyto- kines upon The biomechanies and remodeling of isolated anmion mem- brane, in vitro [J].centa, 2011, 32(3):206-213. 被引量：1
9Mano Y,Shibata K,Sumigama S,et al. Tocilizumab inhibits interleu- kin - 6 - medi - Ated matrix metalloproteinase - 2 and - 9 secretions from human amnion cells in preterm premature repture of membranes [ J]. Gynecol Obstet Invest,2009,68 (3) : 145 - 153. 被引量：1
10Olshan AF. Risk of spontaneous preterm birth is associated with common proinf - lammatory cytokine polymorphisms[ J ]. Epidemiol- ogy,2005,16(4) : 469 -477. 被引量：1