摘要
[目的]探讨影响精神分裂症患者出院后服药依从性的相关因素,为提高依从性制定相应对策.[方法]随机抽取2010年3月-2012年3月自我科出院的精神分裂症患者122例.采用自制影响因素调查表,对影响服药依从性的因素进行调查评定.[结果]服药依从性与文化程度、性别、年龄、婚姻无相关性（P＞0.05）.但完全不依从患者均与存在重大负性生活事件（OR=5.23,95CI 2.00～13.69）、家庭支持差（OR=28.12,95％ CI 7.58～104.31）、不能定期门诊复诊（OR=5.18,95CI 1.56～17.18）、对疾病知识了解差（OR=5.49,95％CI 2.07～14.60）、药物存在副作用（OR=33.60,95％CI 9.29～121.51）和服药种类数量多（OR=4.4495％CI 1.77～11.17）的等因素相关,而部分依从患者与家庭的支持差（OR=5.63,95％CI1.70～18.60）和药物副作用（OR=4.86,95％CI1.62～14.71）等因素有关.[结论]精神分裂症患者院外服药依从性与多种因素有关,完全不依从患者与部分依从患者的这几个因素有所不同,需采取相应措施提高其服药依从性.
[ Objective ] In order to increase the compliance of drug therapy, risk factors associated with incompliance of drug therapy after hospital discharge in schizophrenia patients were explored. [Methods] From 2010 March to 2012 March, 122 cases of schizophrenia were randomly selected after self discharge of hispitalization. Risk factors were assessed using self-made questionnaire for medication compliance. [ Result] No association of compliance of drug therapy with education level, gender, age and marriage were observed. The factors including negative major life events（OR=5.23,95% CI 2.00-13.69）, poor family supports（OR=28.12, 95% CI 7.58± 104.31）, irregular outpatient medication（OR=5.18, 95CI 1.56± 17.18）, poor disease knowledge（OR=5.49, 95% CI 2.07-14.60）, drug side effects（OR=33.60, 95%CI 9.29±121.51） and numbers of drugs taken（OR=4.44, 95% CI 1.77±11.17） were associated with complete incompliance. However, partical incompliance were related with poor family supports（OR=5.63,95% CI 1.70-18.60） and drug side effects （0R=4.86, 95% CI 1.62±14.71）. [Conclusion] Many factors, more in complete incompliance than partical incompliance, may affect the incompliance in patients with schizophrenia after discharge from hospitalization and corresponding measures should be taken to improve medication compliance.
出处
《武警后勤学院学报（医学版）》
CAS
2013年第3期182-184,共3页
Journal of Logistics University of PAP（Medical Sciences）
关键词
精神分裂症
院外
服药依从性
对策
Schizophrenia
Outside the hospital
Medication compliance
Countermeasures
