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左炔诺孕酮宫内缓释系统在临床应用中的研究 被引量:11

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摘要 目的:研究放置左炔诺孕酮宫内缓释系统(曼月乐)在治疗子宫腺肌症的过程中,前后的药物预处理在临床中的疗效。方法:回顾性分析2012年5月至2013年5月于郑州大学第三附属医院门诊放置曼月乐的子宫腺肌症患者120例的临床资料,其中达菲林组40例:放置曼月乐前肌内注射醋酸曲普瑞林(达菲林)3个月;优思明组40例:放置曼月乐后即口服屈罗酮炔雌醇片(优思明)3个月;对照组40例:仅放置曼月乐环。于放置后第1、2、3个月随访,比较3组阴道不规则出血、环脱落等异常情况。结果:使用达菲林组脱环率低于对照组,两组差异有统计学意义(P<0.05);优思明组脱环率与对照组无统计学意义(P>0.05);使用达菲林组阴道不规则出血发生率与对照组比较,差异有统计学意义(P<0.05);优思明组阴道不规则出血发生率低于曼月乐环组,两组差异有统计学意义(P<0.05);而3组痛经程度、月经量比较,差异无统计学意义(P>0.05)。结论:放置曼月乐前使用达菲林可有效预防脱环及减少阴道不规则出血时间,放环之后口服3个月优思明可有效改善阴道不规则出血症状,值得临床上推广应用。
出处 《河南医学研究》 CAS 2014年第3期37-39,共3页 Henan Medical Research
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参考文献7

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共引文献91

同被引文献101

  • 1轩华敏.左炔诺孕酮宫内缓释系统对子宫腺肌症患者月经及卵巢功能的影响[J].临床研究,2015,23(6):107-108. 被引量:5
  • 2侯云虹.宫腔镜下子宫内膜息肉切除术治疗子宫内膜息肉临床效果[J].医学信息,2017,30(6):77-78. 被引量:2
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