摘要
目的通过研究康复疗法对女性心力衰竭(简称心衰)患者运动耐量和心功能的影响,探讨该疗法在女性心衰患者中的应用价值。方法将134例女性心衰患者随机分为对照组(67例)和康复治疗组(简称治疗组,67例),采用6 min步行试验评价运动耐量,运用纽约心脏协会(NYHA)心功能分级和左心室射血分数(LVEF)评价心功能,随访24周,比较两组患者的运动耐量和心功能的差异。结果 (24.0±1.2)周后,对照组61例和治疗组64例患者完成了随访,被纳入最终分析;两组患者基础状态的运动耐量和心功能相近,差异无统计学意义;与对照组相比,治疗组的平均6 min步行距离较长[(403.7±51.4)m vs(355.2±52.4)m,P<0.01],增加量也较大[(145.8±54.8)m vs(63.3±29.6)m,P<0.01];平均NYHA心功能分级低[(2.4±0.4)vs(2.6±0.4),P<0.01)],改善更明显[(-0.4±0.09)vs(-0.1±0.07),P<0.05)];两组平均LVEF差异无统计学意义[(47.3±6.5%)vs(46.4±4.3%),P>0.05)],但改善较对照组显著[(3.7±2.3%)vs(1.0±0.7%),P<0.01)]。结论康复疗法能够显著改善女性心衰患者的运动耐量和心功能,临床效果显著。
[ Objective ] To study the effect of rehabilitation therapy on exercise tolerance and cardiac function in female patients with heart failure （HF}, explore its clinic application value in female HF patients. [ Methods] 134 female HF patients were randomly divided into the control group （ 67 cases ） and the rehabilitation therapy group （ the treatment group, 67 cases ）. The exercise toler- ance was assessed with 6-minute walk test （6MWT） , while the functional classification of NYHA and left ventricular ejection frac- tion （LVEF} were used to evaluate the cardiac function. The patients were followed up for 24 weeks, and the differences in exer- cise tolerance and cardiac function between two groups were compared. [ Results] After 24.0 ± 1.2 weeks, 61 patients in the control group and 64 patients in the treatment group have completed the follow-up, which were included in the final analysis. The exercise tolerance and cardiac function under the basic state were similar in two groups, and the difference was not statistically significant. Compared with the control group, the treatment group had the longer 6MWT distance [ （403.7 ±51.4} m vs （355.2 ± 52.4） m, P 〈0.01 ] and larger increase [ （ 145.8 ±54.8 ） m vs （63.3 ±29.6} m,P 〈0.01 ]. The treatment group displayed lower NYHA classification [ （ 2.4 ± 0.4 } vs （ 2.6 ± 0.41, P 〈 0.01 ] and larger improvement [ （ 43.4 ± 0.09 ） vs （ 43.1 ± 0.07 ）, P 〈 0.05 ]. There was no significant difference in LVEF between two groups [ （47.3 ±6.5% ） vs （46.4 ±4.3% ） ,P 〉0.05], but the in- crease was greater in the treatment group [ （ 3.7 ± 2.3 % ） vs （ 1.0 ± 0.7% } ,P 〈 0.01 ]. [ Conclusion] Rehabilitation therapy can significantly improve exercise tolerance and cardiac function in female HF patients, and the clinical effect is obvious.
出处
《职业与健康》
CAS
2014年第8期1141-1143,1146,共4页
Occupation and Health
关键词
康复疗法
女性
心力衰竭
运动耐量
心功能
Rehabilitation therapy Female Heart failure Exercise tolerance
Cardiac function
