摘要
目的 :探讨食管癌根治术后放射治疗的价值。方法 :1989年 1月— 1994年 6月对 80例食管癌根治术后行术后预防性放疗 ,用配对法与同期单纯手术治疗 80例食管癌进行对比 ,放疗剂量 40— 5 0Gy。结果 :单纯手术组一、三、五年生存率为 76 3%、37 5 %、2 2 5 %。手术放疗组一、三、五年生存率为 77 5 %、5 6 3%、32 5 % ,两组三年生存率有显著性意义 (P <0 0 5 ) ,无淋巴结转移者术后放疗组五年生存率较单纯手术组明显提高 ,有显著差异 (P <0 0 1) ,淋巴结阳性者一、三、五年生存率两组无统计学意义。术后放疗组原发灶复发率为 12 5 % ,单纯手术组为42 5 % ,有显著差异 (P <0 0 1)。结论 :术后放疗后复发率低 ,无淋巴结转移者术后应放疗 。
Purpose:To evaluate radiotherapy after operation of esophageal carcinoma. Methods:A comparative study was done between the group of 80 patients treated by postoperative radiotherapy and the group of 80 patients by operation only from January 1989 to June 1994. The radiation dose was 40—50 Gy. Results:The 1 ,3 ,and 5 year survival rates of operative group were 76.3%, 37.5%, 22.5%, and those of postoperative radiotherapy were 77.5 %,56.3 %,32.5 %. There was significant difference between the 3 year survival rates of the two groups ( P <0 05). In the patients without lymph ndoes metastases,5 year survival rates were markedly higher in the group of patients treated by operation with postoperative radiotherapy than in the group of patients treated by operation only ( P <0 01). For patients with lymph nodes metastase, there was no significant difference between the two groups. The recurrence rate of the primary disease was obviously lower in those who received postoperative radiotherapy than those who did not ( P <0 01).Conclusions:The incidence of recurrence is lower in those who received postoperative radiotherapy than those who did not.The patients without lymph nodes metastase should be irradiated after operation. The 3 year survival rate is higher in patients who received postoperative irradition. [
出处
《中国癌症杂志》
CAS
CSCD
2001年第1期65-66,共2页
China Oncology
