摘要
目的探讨米力农在婴幼儿法洛氏四联症根治术后防治低心排出量综合征(低心排)的疗效。方法将法洛氏四联症根治术后的婴幼儿随机分成米力农组与对照组(多巴酚丁胺组),分别静脉泵入米力农与多巴酚丁胺治疗。观察2组病例临床症状、体征、心电图、心率(HR)、血压(取体循环收缩压SBP),并用超声心动图测左室射血分数(LVEF)、左室舒张末径(LVSD)、心脏指数(CI)等有关心功能指标。结果两组治疗前后临床疗效和心功能指标比较有统计学意义(P<0.05)。米力农组LVEF、LVSD、CI等心功能指标治疗后比较差异有显著性(P<0.01),HR、SBP无显著变化(P>0.05),无心律失常的发生。结论米力农防治婴幼儿法洛氏四联症根治术后早期低心排出量综合征有确切疗效。
Objective：To explore Milrinone curative effect on prevention of low cardiac output syndrome after total correction of tetralogy of FaUot in infants. Methods ： The infants were divided into the Milrinone group and the control group （dobutamine group）randomly after total correction of tetralogy of Fallot, and pumped into vein with Milrinone and dobu- tamine separately. The 2 groups of eases were observed, including clinical symptoms, physical signs, electrocardiogram, heart rate and blood pressure（ choose systolic blood pressure SBP）, meanwhile the relevant heart function index about left ventricular ejection fraction（LVEF） , left ventricular end-diastolic diameter（LVSD） and cardiac index（CI） were measured by echocardiography. Results：In comparison between the two groups before and after treatment, clinical efficacy and cardi- ac function indexes were of statistical significance（ P 〈 0.05 ）. Index of heart function such as LVEF, LVSD and CI after treatment had significant difference in Milrinone group （P 〈 0.01 ）. Heart rate and SBP showed no significant change（ P 〉 0.05 ）. There was no occurrence of arrhythmias. Conclusion ： Milrinone has exact effect on prevention of low cardiac output syndrome in Milrinone early applications in infant after total correction of tetralogy of Fallot .
出处
《泰山医学院学报》
CAS
2014年第1期30-32,共3页
Journal of Taishan Medical College
关键词
米力农
婴幼儿
法洛氏四联症根治术
低心排出量综合征
Milrinone
infant
total correction of tetralogy of Fallot
low cardiac output syndrome
