摘要
目的研究年龄、性别、学习效应及短期波动对健康人在闪烁视野检查中的影响。方法研究1组使用Octopus-900全视野计对2011年7月至2013年3月期间在青岛大学医学院附属黄岛分院门诊就诊的39例未发现异常者单眼进行闪烁视野检查，并以性别分别比较平均闪烁临界融合频率（Criti-cal flicker fusion frequency，CFF），采用线性回归分析法分析年龄对CFF的影响。研究2组对2012年9一10月期间招募的14名健康成年人在青岛大学医学院附属黄岛分院进行CFF检测，所有受检者在1个月内共进行5次检查，其中前3次检查每次间隔15d。从第3次检查开始至第5次检查，每次间隔15min。比较CFF各次检测数值，研究学习效应对闪烁视野检查的影响，分析个体间、个体内短期波动。结果研究1组男女性别的CFF检查结果差异无统计学意义（P〉0．05）。线性回归分析提示CFF值与年龄呈线性相关，随年龄增长CFF值降低。研究2组检查时间、假阳性率及可信因子（reliablefactor，RF）在不同的检查时段差异有统计学意义（P〈0．05）。通过学习，可缩短检查时间，降低假阳性率，并增加检查的RF，提高CFF平均值。结论性别对CFF检查结果的影响差异无统计学意义。随年龄增长CFF值呈下降趋势。经过学习，可提高闪烁视野检查的准确性和敏感性。在短时间内，闪烁视野检查存在适度的波动。
Objective To study the influence of age, gender, learning effect and short-term fluc- tuation for healthy subjects using flicker perimetry. Methods Research one, 39 healthy subjects had taken flicker perimetry （critical flicker perimetry, CFF） by using Octopus-900 perimeter （Haag-Stre- it-Switzerland） during July, 2011 to March, 2013 in West coast medical center of Qingdao university medical college. Mean CFF values were compared between genders, and the influence of age was evaluated by linear regression analysis. Research two, 14 healthy adults had taken flicker perimetry （critical flicker fusion frequency, CFF） by using Octopus-900 perimeter （Switzerland Haag-Streit Com- pany） during September to October 2012 in West coast medical center of Qingdao university medi- cal college. All subjects were taken flicker perimetry in one eye 5 times in one month. First three sessions were taken per 15 days. Last three sessions were taken in the same day per 15 minutes. Mean CFF values were compared among the five times, then the influence of learning effect and short-term fluctuation were evaluated. Result Research 1： There were no statistically significant dif- ferences in mean critical flicker fusion frequency values between males and females （P 〉0.05）. Lin- ear regression analysis demonstrated that critical fusion frequency significantly decreased with age （P 〈0.05）. Research 2： Examination time, false positive response and reliable factor in first time were significantly different from the other times. By learning, subjects could shorten the examination time, reduce the RF, and improve the mean CFF values. Conclusions Flicker perimetry is influ- enced by age, learning-effect and short-term fluctuation, so all the above factors need to be consid- ered when checking the result of perimetry. No influence on flicker perimetry is occurred by gender. More research conclusions should be obtained to describe flicker perimetry whether other factors could influence, and of value in diagnosing dis
出处
《中国实用眼科杂志》
CSCD
北大核心
2014年第4期443-449,共7页
Chinese Journal of Practical Ophthalmology
关键词
闪烁视野
闪烁临界融合频率
学习效应
短期波动
Flicker perimetry
Critical flicker fusion frequency
Learning effect
Short-term fluc-tuation
