摘要
目的 :探讨静脉注射恩丹西酮的时机和剂量对吸静复合全麻上腹部手术患者术后恶心呕吐的预防效果。方法 :15 0例ASAⅠ～Ⅲ级成人患者随机分成五组。A组 :麻醉诱导前静脉注射恩丹西酮 4mg ,B组 :麻醉诱导前静脉注射恩丹西酮 8mg ,C组 :术毕静脉注射恩丹西酮 4mg ,D组 :术毕静脉注射恩丹西酮 8mg ,E组不用恩丹西酮。结果 :A、B、C、D、E组患者术后恶心呕吐发生率分别为 5 0 .0 % ,40 .0 % ,5 3 .3 % ,16 .7% ,5 6 .7% (P <0 .0 1)。结论 :术毕静脉注射恩丹西酮 8mg更能有效预防全麻上腹部术后恶心呕吐。
Objective:To evaluate the prophylactic effect of ondansetrom (OND) on postoperative nausea and vomiting (PONV).Methods:One hundred and fifty patients,scheduled for upper abdominal surgery under general anesthesia,were randomly allocated into five groups.Group A OND 4mg iv before anesthesia induction,Group B OND 8mg iv before anesthesia induction,Group C OND 4mg iv after operation,Group D OND 8mg iv after operation,and Group E without OND. Results:The incidences of nausea and vomiting in group A,B,C,D,E were 50.0%,40.0%,53.3%,167%,56.7% respectively (P<0.01).Conclusions:Ondansetron 8mg iv after operation can be used effectively to prevent PONV in upper abdominal surgical patients.
出处
《中国现代医学杂志》
CAS
CSCD
2001年第2期44-45,共2页
China Journal of Modern Medicine
