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中药板蓝根中高级不饱和脂肪酸的分离鉴定及免疫活性成分的研究 被引量:22

ISOLATION OF HIGHER UNSATURATED FATTY ACIDS AND STUDY OF IMMUNOLOGICALLY COMPETENT CONSTITUENTS FROM ISATIS TINCTORIA L
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摘要 从十字花科植物菘蓝 (IsatistinctorialL .)的根中首次分离鉴定出一组含有三种分子的高级不饱和脂肪酸 ,命名为板蓝根组酸。并发现其对人多形核细胞 (PMN)氧化作用及化学发光具有激活作用 。 Objective:To make isolation of a fraction and its subfractions from ′Banlangen′,root of Isatis tinctoria L.,and study their immunocompetence.Methods:A fraction 3 and its subfractions were isolated from ′Banlangen′with dry-column flash chromatography.It was tested that the effect of those fractions on chemiluminescence(CL) reaction of human polymorphonuclear cells (PMN).Results:A group of higher unsaturated fatty acids that contain three different moleuculse were isolated and elucidated from ′Banlangen′for the first time and was named Banlangen-acids.A two-way immunocompetence was found form fraction 3 and its subfractins.Conclusion:There are some anti-inflamation components in fraction 3 and its subfractions from ′Banlangen′.Banlangen-acids take an important role in it.
出处 《中国现代医学杂志》 CAS CSCD 2001年第1期15-16,共2页 China Journal of Modern Medicine
基金 中国 -丹麦科技合作协议Danida资助项目!(项目编号AM 9:3) 广西教育厅资助项目
关键词 板蓝根 板蓝根组酸 人多形核细胞 化学发光 <Keywords>Isatis Indigotica L Banlangen-acids Dry-column Flash Chromatography Polymorphonuclear(PMN) Chemiluminescence(CL)
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