摘要
目的探讨ICU感染性休克病死的相关影响因素,对临床ICU患者的治疗提供可靠依据。方法选择2007年1月-2013年1月ICU收治的感染性休克患者96例,对其临床资料进行回顾性分析,根据患者的治疗结局将患者分为死亡组54例、存活组42例,对两组患者的各因素进行比较,数据采用SPSS 16.0软件进行分析。结果单因素分析结果显示,死亡组和存活组患者在年龄、APACHEⅡ评分、MODS数目、SIRS数目、平均动脉压、免疫功能、是否接受有创检查上差异均有统计学意义(P<0.05);多因素logistic回归分析结果显示,MODS数目、APACHEⅡ评分以及SIRS数目进入回归模型(P<0.05),是ICU感染性休克病死的独立危险因素。结论 APACHEⅡ评分、MODS及SIRS数目是ICU感染性休克病死的独立危险因素,采取积极的综合治疗措施、调控患者的炎症反应并及早给予患者支持疗法以保护其器官功能,是降低ICU感染性休克病死率的有效措施。
OBJECTIVE To investigate related factors for ICU patients died of septic shock and provide a reliable basis for the clinical treatment of ICU patients .METHODS Ninety-six patients with septic shock admitted in ICU during Jan .2007-2013 were selected .Their clinical data were retrospectively analyzed .The patients were divided into death group of 54 patients and survival group of 42 patients according to treatment outcomes .Various factors were compared for the two groups of patients ,data were analyzed using the software SPSS 16 .0 .RESULTS The univariate analysis showed that there were statistically significant differences in age ,APACHE Ⅱ score ,MODS number ,SIRS numbers ,mean arterial pressure ,immune function ,and invasive checks between death group and survival groups （P＆lt;0 .05 ） .The multivariate logistic regression analysis showed that ,MODS number ,APACHEⅡ score and the number of SIRS into the regression model were the independent risk factors for death of patients with septic shock in ICU （P＆lt;0 .05） .CONCLUSION MODS number ,APACHE Ⅱ score and the number of SIRS were independent risk factors for death of patients with septic shock in ICU .Effective measures to reduce mortali-ty of patients with septic shock in ICU included active measures to regulate the inflammatory response in patients and supportive therapy given to patients as soon as possible to protect their organ function .
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2014年第7期1662-1664,共3页
Chinese Journal of Nosocomiology
基金
浙江省自然科学基金资助项目(211098)
