摘要
目的 :分析足叶乙甙、甲氨蝶呤、顺铂 (EMP)方案治疗绒癌耐药病例的疗效 ,评价此方案的临床应用价值。方法 :回顾性分析了 2 4例绒癌耐药病例应用 EMP方案治疗后的临床疗效及毒副反应。结果 :2 4例经平均 6 .4个疗程化疗 ,15例获完全缓解 (6 2 .5 % ) ,6例部分缓解 (2 5 % ) ,3例无效 (12 .5 % )。完全缓解后复发率为 6 .7%。结论 :EMP是治疗耐药滋养细胞肿瘤的安全。
Objective:To evaluate the effectiveness and toxicity of combination chemotherapy with methotrexate,etopside and cispltain(EMP)for the treatment of chemorefractory choriocarcinoma.Methods:Twenty four patients of chemorefractory choriocarcinoma were treated with EMP regimen.The clinic effectiveness and toxicity were assessed after treatment .Results:The twenty four patients received 154 cycles of the study regimen,the median number of courses for each patients was 6.4.Fifteen cases(62.5%)achieved a complete remission.Six cases(25%)had a partial remission.Three (12.5%)showed nonresponse.Conclusion:EMP is an effective and safe regimen for the treatment of chemorefractory gestational trophoblastic tumor.It can be selected for treating chemorefractory choriocarcinoma.
出处
《实用妇产科杂志》
CAS
CSCD
北大核心
2001年第1期28-29,共2页
Journal of Practical Obstetrics and Gynecology
