摘要
目的 调查长沙市社区老年人轻度认知功能障碍（MCI）的患病率并分析其相关因素.方法 采取多阶段随机整群抽样的方法,于2012年4-9月在长沙市5个区随机抽取2个区,每个区再随机抽取1个街道,每个街道随机抽取2个社区,共调查了1 764例老年人.采用简易智能精神状态量表（MMSE）、北京版蒙特利尔认知评估量表（MoCA）、总体衰退量表（GDS）、临床痴呆评定量表（CDR）、日常生活能力量表（ADL）对老年人进行MCI初步筛查,然后再由神经内科专家依据临床MCI诊断标准确诊.计算MCI患病率,比较不同人口学特征的老年人MCI患病率,采用Logistic回归分析MCI患病率的相关因素,并与其他城市的老年人MCI患病率进行比较.结果 长沙市社区老年人MCI患病率为16.27%（287/1 764）.随着年龄的增加,MCI患病率增加[60~、70~、80~岁分别为9.79%（84/858）、20.14%（149/740）和32.53%（54/166）,P＜0.05];教育程度越高,MCI患病率越低[文盲、小学、初中、高中或中专、大专、本科及以上分别为32.10%（26/81）、18.40%（90/489）、13.97%（70/501）、15.29%（61/399）、14.39%（19/132）和12.96%（21/162）,P＜0.05];体力劳动者MCI患病率高于脑力劳动者[19.12%（187/978）与12.72%（100/786）,P＜0.05];独居者MCI患病率高于非独居者[21.59%（65/301）与15.17%（222/1 463）,P＜0.05].Logistic回归分析显示,年龄、文化程度、婚姻状况进入回归方程（P＜0.05）.长沙市社区老年人MCI患病率与葡萄牙、新加坡、北京、乌鲁木齐的MCI患病率无差异（P＞0.05）,但却低于上海[35.78%（161/450）],高于成都[2.35%（92/3 910）]（P＜0.05）.结论长沙市社区老年人MCI患病率处于中等水平,高龄、文化程度低、无配偶的老年人是MCI的高危人群,应对其重点防护.
Objective To investigate the prevalence and factors associated with mild cognitive impairment（MCI） among the elderly in Changsha communities.Methods From April to September in 2012,a multi-stage random cluster sampling method was used to select two zones from five zones in Changsha,then two streets were randomly selected from the above two zones respectively.Finally,we selected two communities from each street,totally we got 4 communities,and a total of 1 764 elderly were investigated.MMSE,MoCA,GDS,CDR and ADL were used to screen MCI among the ederly,and then MCI was confirmed by a neurology specialist according to clinical diagnostic criteria for MCI.MCI prevalence was calculated,MCI prevalences of the elderly with various demographic characteristics were compared.Logistic regression analysis was used to identify the risk factors for MCI,MCI prevalences were compared between study group and the elderly of other cities.Results MCI prevalence of the elderly in Changsha communities was 16.27%（287/1 764）.With increasing age,MCI prevalence increased[MCI prevalence among 60~,70~,80~ year-old group was 9.79%（84/858）,20.14%（149/740） and 32.53%（54/166） respectively,P〈0.05];With higher level of education,MCI prevalence was lower[MCI prevalence among illiterate,elementary,middle,high school or technical secondary school,junior college,college and above group was 32.10%（26/81）,18.40%（90/489）,13.97%（70/501）,15.29%（61/399）,14.39%（19/132） and 12.96%（21/162） respectively,P〈0.05];MCI prevalence in manual laborers[19.12%（187/978） ] was significantly higher than that in mental workers[12.72%（100/786）,P〈0.05];MCI prevalence among solitary was significantly higher than that among non-solitary[21.59%（65/301） vs.15.17%（222/1 463）,P〈0.05].Logistic regression analysis showed that age,educational level,marital status were in the regress equation（P〈0.05）.There was no significant difference in MCI prevalence among the elderly in Changsha communities and the elderly i
出处
《中国全科医学》
CAS
CSCD
北大核心
2014年第9期1031-1035,共5页
Chinese General Practice
基金
湖南省自然科学基金项目(11JJ5057)
关键词
老年人
认知障碍
患病率
危险因素
长沙市
Aged
Cognitive disorders
Prevalence
Risk factors
Changsha city
