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结构DNA纳米新技术的研究现状与应用

Research status and application of structural DNA nanotechnology
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摘要 综述了结构DNA纳米技术——DNA自组装、DNA折纸术和SST自组装的研究现状,并以郑州轻工业学院校徽设计中引入DNA折纸术构建校徽DNA结构模型、利用SST自组装方法设计构造镂空结构的校徽图形为例,对结构DNA纳米技术予以评析与探讨;鉴于该技术目前主要应用于引导无机纳米粒子精确装配、装备纳米生物芯片以及与微加工技术相结合等方面,提出:纳米电子电路及器件、纳米光电子学、高灵敏度高特异性生物传感器、分子机器人、材料学和纳米医学等领域,将是结构DNA纳米技术应用未来的发展方向. Structural DNA nanotechnology was systematic summarized, including the research status of DNA self-assembly, DNA origami and SST self-assembly. In the design of Zhengzhou University of Light Industry badge for instance, DNA origami and SST self-assembly were introduced to devise and establish DNA struc- tural model of school badge with hollow structure. With this example, structural DNA nanotechnology was valued and investigated. The main application of the technique was in the aspects of the assembly of guiding inorganic nanoparticles with precision, the equipment of nano-bio-chip, as well as the combination with micro-machining technology. In view of this it was proposed that structural DNA nanotechnology would play a more active role in the application field of nano-electronic circuits and devices, nano-optoelectronics, bio- sensors of high sensitivity and high specificity, molecular robotics, materials science and nano-medicine etc. in future development.
出处 《郑州轻工业学院学报(自然科学版)》 CAS 2014年第1期7-14,共8页 Journal of Zhengzhou University of Light Industry:Natural Science
基金 国家自然科学基金项目(61070238 61272022 U1304620) 河南省基础与前沿技术研究计划项目(122300413211 132300410183) 河南省创新型科技人才队伍建设工程支持项目(124200510017) 郑州市科技人才队伍建设计划(科技领军人才)项目(131PLJRC648) 河南省教育厅科学技术研究重点项目(13A413371)
关键词 结构DNA纳米技术 DNA自组装 DNA折纸术 SST自组装 structural DNA nanotechnology DNA self-assembly DNA origami SST self-assembly
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