摘要
目的：探讨后循环缺血性眩晕急性发作期证候相关危险因素。方法：收集226例后循环缺血性眩晕急性发作期患者的一般资料和四诊信息,用因子分析的方法观察证候分布情况,用logistic回归分析探索各证候类型的相关危险因素。结果：八类主要证候的相关危险因素：气虚证为颈椎病病史[OR=2.542,95%CI（1.167-5.538）,P=0.019];肝阴虚证为年龄层次[OR=1.688,95%CI（1.076-2.650）,P=0.023];热证为高血压病史[OR=4.864,95%CI（1.738-13.615）,P=0.003];风痰证为酗酒[OR=5.575,95%CI（1.050-29.615）,P=0.044]及低头伏案工作[OR=2.532,95%CI（1.232-5.204）,P=0.011];气血两虚证为生活安逸[OR=5.106,95%CI（1.123-23.208）,P=0.035]及久站[OR=5.006,95%CI（1.520-16.488）,P=0.008];脾虚湿阻证为眩晕家族史[OR=9.848,95%CI（2.264-42.829）,P=0.002）及电脑前工作[OR=3.246,95%CI（1.039-10.139）,P=0.043）;肝郁化火证为焦虑状态[OR=4.563,95%CI（1.508-13.810）,P=0.007）;肝郁痰热证为较小的工作压力[OR=3.533,95%CI（1.185-10.532）,P=0.024]及饮酒[OR=2.822,95%CI（1.093-7.286）,P=0.032]。结论：探索证候相关危险因素可为后循环缺血性眩晕急性发作期的辨证论治提供参考。
Objective： To investigate the risk factors related to posterior circulation ischemic（ PCI） vertigo syndromes in acute stage. Methods： Logistic regression analysis was used to observe the correlation between syndromes and baseline data of 226 patients suffering from PCI vertigo. Results： The risk factor of Qi deficiency syndrome was cervical spondylosis [odds ratio（ OR） = 2. 542,95% confidence interval（ CI）,1. 167- 5. 538,P = 0. 019]; the risk factor of liver Yin deficiency syndrome was age level（ OR = 1. 688,95% CI,1. 076 - 2. 650,P = 0. 023）; the risk factor of heat attacking syndrome was hypertension（ OR = 4. 864,95% CI,1. 738 - 13. 615,P = 0. 003）; the risk factors of wind- phlegm syndrome were alcoholism（ OR = 5. 575,95% CI,1. 050 - 29. 615,P = 0. 044） and sedentary working（ OR = 2. 532,95% CI,1. 232 - 5. 204,P = 0. 011）; the risk factors of Qi- blood deficiency syndrome were excessive leisure（ OR = 5. 106, 95% CI,1. 123 - 23. 208,P = 0. 035） and long- term stand（ OR = 5. 006,95% CI,1. 520 - 16. 488,P = 0. 008）; the risk factors of syndrome dampness stagnancy due to spleen deficiency were family history of vertigo（ OR = 9. 848,95% CI,2. 264 - 42. 829,P = 0. 002） and work with computers（ OR = 3. 246,95% CI,1. 039 - 10. 139,P = 0. 043）; the risk factor of liver Qi obstruction with pathogenetic fire syndrome was anxiety state（ OR = 4. 563,95% CI 1. 508 - 13. 810, P = 0. 007）; the risk factors of liver Qi obstruction with phlegm- heat disturbance syndrome were less working stress（ OR =3. 533,95%CI,1. 185 -10. 532,P =0. 024） and drinking（ OR =2. 822,95%CI,1. 093 -7. 286,P =0. 032）. Conclusion： It suggests that the relationship between the risk factors of PCI vertigo and syndromes in acute stage should support the syndrome differentiation and treatment.
出处
《中医药学报》
CAS
2014年第1期107-111,共5页
Acta Chinese Medicine and Pharmacology
基金
首都特色技术发展研究项目(No.Z090507017709025)
北京中医药大学科研创新团队(2011-CXTD-23)
关键词
眩晕
后循环缺血
急性发作
证候
危险因素
Vertigo
Posterior circulation ischemia
Acute stage
Syndrome
Risk factor
