摘要
糖皮质激素具有许多作用,广泛运用于临床,包括结核病的治疗。但是糖皮质激素在结核病治疗方面是一把双刃剑,既可辅助治疗结核,减轻症状,改善预后,也可导致结核播散和复发。不过,合理利用糖皮质激素,严格掌握其适应证,可改善结核病预后,降低其死亡率。根据专家共识和文献资料,肺结核或合并顽固性咯血、结核性浆膜炎、结核性脑膜炎、变态反应综合征、气管支气管结核、抗结核药所致严重过敏反应和结核病合并其他需糖皮质激素治疗的疾病均可酌情运用糖皮质激素,获得更好疗效。
Glucocorticoids, which have many functions, are widely used in clinical practice, including the treatment for tuberculosis. However, just as every coin has 2 sides, glucocorticoids can alleviate symptoms and improve progno- sis and be in the adjunctive treatment of tuberculosis, it can also spread mycobacterium tuberculosis and make it recur. If glucocorticoids can be used reasonably within specific indications, it will improve prognosis and mortality rates will be lower. According to expert consensus and literature, it is necessary to use glucocorticoids for tuberculosis, includ- ing pulmonary tuberculosis, refractory hemoptysis, tuberculosis serositis, tuberculosis meningitis, allergy syndrome, endobronchial tuberculosis, serious anaphylaxis caused by antituberculosis drugs and tuberculosis with other diseases which need glucocorticoids.
出处
《中南药学》
CAS
2014年第1期89-92,共4页
Central South Pharmacy
关键词
糖皮质激素
结核病
免疫
glucocorticoid
tuberculosis
immunity
