摘要
目的:探讨辛伐他汀联合加味小陷胸汤治疗高脂血症的临床疗效。方法:90例高脂血症患者按随机数字表法分为观察组和对照组,每组各45例。观察组给予辛伐他汀联合加味小陷胸汤治疗,对照组给予辛伐他汀治疗。观察并对比两组治疗前后血脂和血液流变学变化,评价两组的临床疗效。结果:治疗前两组血脂和血液流变学比较,无显著性差异(P>0.05),治疗后两组血脂和血液流变学指标均较本组治疗前明显改善,且观察组治疗后改善情况明显优于对照组,差异均具有统计学意义(P<0.05)。观察组有效率为93.33%明显高于对照组的82.22%,差异有统计学意义(P<0.05)。治疗期间两组均未发现明显不良反应。结论:辛伐他汀联合加味小陷胸汤治疗高脂血症临床疗效显著且安全可靠。
Objective ： To investigate the clinical curative effect of hyperlipidemia treated by Simvastatin combined with Modified Xiaox- ianxiong Decoction. Methods： 90 cases of patients with hypedipidemia were divided into the observation group and the control group, each of 45 cases. The Observation group was treated with Simvastatin and Modified Xiaoxianxiong Decoction,and the control group was given Simvastatin. Observed and compared the blood lipid and blood rheology of the two groups before and after treatment, and evaluated the clinical curative effect of two groups. Results ： Before treatment, there were no significant difference between the blood lipid and blood rheology test results of the two groups （ P 〉 O. 05 ）. After treatment,the blood lipid and blood rheology of the two groups were obviously improved compared with before treatment separately, and the improvement situation of observation group was better than that of control group, and the difference has statistical significance （P 〈 0.05 ）. The effective rate of observation group was 93.33% which was obvi- ously higher than that of control group 82.22%, and the difference has statistically significance （ P 〈 0.05 ）. The two groups were not found obvious adverse reactions during the treatment. Conclusion： The clinical curative effect of hyperlipidemia treated by Simvastatin combined with Modified Xiaoxianxiong Decoction was significant and safe and reliable.
出处
《中医学报》
CAS
2014年第4期566-568,共3页
Acta Chinese Medicine
基金
国家自然科学基金项目(编号:81102587)
关键词
高脂血症
辛伐他汀
加味小陷胸汤
hyperlipidemia
simvastatin
modified xiaoxianxiong decoction
