摘要
目的应用左心房追踪(LAVT)技术评价继发孔型房间隔缺损(S-ASD)患者介入封堵术后左心房容积和功能变化。方法运用LAVT技术获得30例介入封堵成功的S-ASD患者术前3天、术后3天、术后3个月时的左心房容积-时间曲线和容积变化速率曲线,记录容积-时间曲线上的左心房最大容积(LAVmax)、左心房收缩前容积(LAVpre)、左心房最小容积(LAVmin),并用体表面积(BSA)进行校正,得到相应的容积指数LAVImax、LAVIpre、LAVImin,计算左心房总体、被动、主动排空量(LAVItotal、LAVIpass、LAVIact),左心房被动、主动排空分数(LAVIpEF、LAVIaEF),记录左心房容积变化速率曲线上的收缩期充盈速率峰值(dv/dtS),舒张早期、舒张晚期的排空速率峰值(dv/dtE、dv/dtA)。比较术前3天、术后3天、术后3个月各参数的差异。结果术后3个月,LAVImax、LAVIpre、LAVImin及LAVItotal较术前3天明显降低(P均<0.05),LAVIaEF、dv/dtA较术前3天明显升高(P均<0.05);LAVIpass、LAVIpEF、LAVIact、dv/dtS、dv/dtE在术后3天、术后3个月及术前3天的差异均无统计学意义(P均>0.05)。结论介入封堵S-ASD可有效改善心房功能;LAVT技术能够准确、快速加以评价。
Objective To evaluate left atrial （LA） volume and function by using left atrial volume tracking （LAVT） method in patients with secundum atrial septal defect （S-ASD） after transcatheter closure. Methods Totally 30 patients with S-ASD were collected, and their LA volume-time curve and emptying fraction curve were obtained 3 days before tran- scatheter closure, 3 days and 3 months after transcatheter closure by using LAVT method. LA maximal volume （LAVmax）, LA pre-systolie volume （LAVpre）, LA minimal volume （LAVmin） from volume-time curve were recorded. Then the body surface area （BSA） was used to revise these volume indexs （LAVImax, LAVIpre, LAVImin）. The empty- ing function parameters were calculated and recorded, i.e. LA total emptying volume （LAVItotal）, LA passive emptying volume （LAVIpass）, LA active emptying volume （LAVIact）, LA passive emptying fraction （LAVIpEF）, LA active emp- tying fraction （LAVIaEF）, LA filling peak （dv/dtS）, early diastolic LA emptying peak （dv/dtE） and late diastolic LA emptying peak （dv/dtA） from emptying fraction curve. The differences of the above parameters among 3 time points were compared. Results Three months after transcatheter closure, LAVImax, LAVIpre, LAVImin, LAVItotal decreased, LAVIaEF, dv/dtA significantly increased compared with those for three days before transcatheter closure （all P^0. 05）. LAVIpass, LAVIpEF, LAVIact, dv/dtS, dv/dtE were not significantly different before and after transcather closure of S-ASD. Conclusion LA function in S-ASD patients can be significantly improved after transcatheter closure, and LA vol- ume and function can be accurately and quickly evaluated using LAVT method.
出处
《中国医学影像技术》
CSCD
北大核心
2014年第4期518-521,共4页
Chinese Journal of Medical Imaging Technology
关键词
房间隔缺损
心房功能
左
介入封堵术
左心房追踪
Heart septal defects, atrial
Atrial function, left
Transcather closure
Left atrial volume tracking
