摘要
目的:探讨百炎净联合黄连素对鼻咽癌放疗患者皮肤损伤的影响。方法:将76例鼻咽癌放疗患者随机分为实验组和对照组各38例,对照组在患者颈部照射野皮肤处使用聚维酮碘,实验组使用百炎净联合黄连素,比较两组不同时间段发生Ⅰ度放射性皮肤损伤情况及放疗第6周放射性皮肤损伤程度。结果:两组不同时间段发生Ⅰ度放射性皮肤损伤情况及放疗第6周放射性皮肤损伤程度比较差异有统计学意义(P<0.05)。结论:采取局部预防性干预措施,可减轻鼻咽癌放疗患者皮肤放射性损伤。百炎净联合黄连素对鼻咽癌放疗患者的皮肤有防护作用,值得临床推广。
Objective:To investigate the effect of compound SMZ combined with berberine on the injury of skin of nasopharyngeal cancer patients with radiotherapy .Methods:76 nasopharyngeal cancer patients were randomly divided into the experimental group and the control group (38 cases in each group).Povidone iodine was daubed around the irradiation field of the patient &#39;s neck in the control group;com-pound SMZ combined with berberine was used in the experimental group .First-degree radioactive skin injury of the patients in different time-range and the degree of skin injury on the 6th week of radiotherapy were compared between the two groups .Results:There were sta-tistically significant differences in the comparison of first -degree radioactive skin injury in different time -range and the degree of skin in-jury on the 6th week of radiotherapy between the two groups (P〈0.05).Conclusion:The local preventive intervention measures can reduce the radiation injury of skin of radiotherapy in patients with nasopharyngeal cancer .The compound SMZ combined with berberine has a pro-tective effect on the patient&#39;s skin in radiotherapy .
出处
《齐鲁护理杂志》
2014年第8期14-16,共3页
Journal of Qilu Nursing
基金
2013年度湛江市第三批非资助科技攻关计划项目(2013B1199)
关键词
鼻咽癌
放疗
放射性皮炎
Nasopharyngeal cancer
Radiotherapy
Radiation dermatitis