摘要
Objec ve To observe the effi cacy of electroacupuncture on glycometabolism disturbance in metabolism syndrome. Methods With matched-pairs design,80 pa ents mee ng with the diagnos c criteria for glycometabolism abnormali es were randomized into the group combining acupuncture and medica on（group A） and the western medicine group（group B）,and 40 pa ents were included in each group. Electroacupuncture was carried out on back-shu points,Zúsānlǐ（足三里 ST 36）,Zhōngwǎn（中脘 CV 12）,Sānyīnjiāo（三阴交 SP 6） and other acupoints for group A,needles were retained for 20 min except back-shu points,once a day,con nuous ten mes as a treatment course,the next treatment course was started a er an interval for 3–5 days,and totally 3 treatment courses were carried out; furthermore,the pa ents were orally administered with Glucotrol XL and felodipine,5 mg each,once a day. The pa ents in group B were treated simply with drugs（the medica on was the same to that for the group A）. Body mass index（BMI）,related biochemical indices and blood pressure of the pa ents were measured before and a er the interven on,respec vely. Results BMI,blood-fas ng glucose,blood glucose 2 h after meal,fasting insulin,insulin resistance index,systolic pressure and diastolic pressure in group A all significantly improved in comparison to those before the electroacupuncture intervention（P0.01）. The difference in BMI in group B before and after the treatments was not statistically significant（P0.05）,and other indices all showed significant improvements（P0.01）. The improvements in the indices as mentioned above in the group A after treatment were significantly better than those in the group B（P0.01）. Conclusion Electroacupuncture intervention can significantly reduce weight,combina on of acupuncture and medica on shows be er effi cacy in reducing blood glucose,improving insulin sensi vity and insulin resistance in comparison to simple administra on with medica ons.
目的：观察电针干预治疗代谢综合征糖代谢紊乱的效果。方法：将符合糖代谢异常诊断标准80例患者按随机化配对设计分为针药组和西药组,每组40例。针药组采用背俞穴、足三里、中脘、三阴交等穴电针治疗,背俞穴不留针,余穴留针20 min,每日1次,连续10次为一疗程,休息3-5 d再行下1个疗程,共治疗3个疗程;另外,口服瑞易宁、非洛地平,均为5 mg,每日1次。西药组采用单纯药物治疗（同针药组药物治疗）。分别于干预前后检测患者体质量指数（BMI）、相关生化指标、血压。结果：针药组电针前后比较,BMI、空腹血糖、餐后2 h血糖、空腹胰岛素、胰岛素抵抗指数、收缩压、舒张压均明显改善（P〈0.01）。西药组治疗前后比较,BMI差异无统计学意义（P〉0.05）,其余指标均有明显改善（P〈0.01）。治疗后针药组上述指标的改善程度均明显优于西药组（P〈0.01）。结论：电针干预能够明显减轻体质量,针药并用较单纯使用药物具有更好的降低血糖、提高胰岛素敏感性、改善胰岛素抵抗的作用。
基金
Supported by scien fic and technological tackling project in Administra on of TCM of Health Bureau of Hebei Province:2009099
