摘要
干燥综合征(Sjgren’s syndrome,SS)是一种以侵犯外分泌腺为主的自身免疫性疾病,其发病机制可能与抗毒蕈碱乙酰胆碱3受体抗体(anti-M3R antibody,抗M3R抗体)相关,本文通过抗M3R抗体与毒蕈碱乙酰胆碱3受体(M3R)的结合表位,以及与SS的临床表现、治疗的关系,对抗M3R抗体在SS中的致病作用进行综述。
Sjogren＇s syndrome is an autoimmune disease mainly involving exocrine glands. It＇s pathogenesis may be related to autoantibodies against type 3 muscarinic acetylcholine receptor. The progress of the correlation between anti-M3R antibody and the pathogenesis of SS through the instructions from the epitope combined with anti-M3R an- tibody, the relationship between anti-M3R antibody and the pathogenesis, clinical manifestation and treatment of Sjogren＇s syndrome were reviewed in this paper.
出处
《皮肤病与性病》
2014年第2期76-78,共3页
Dermatology and Venereology
