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牙周炎临床检测指标与龈沟液Ⅰ型胶原羧基端交联肽的关系 被引量:7

The relationship between C-terminal telopeptides of type I collagen in GCF and periodental indexes
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摘要 目的:探讨龈沟液中I型胶原羧基端交联肽(C-terminal telopeptides of type I collagen,CTX)水平与常用牙周炎临床检测指标的相关性。方法:选择就诊牙周病患者60例的77颗牙齿,采用酶联免疫吸附法测定其龈沟液中CTX水平,并对临床牙周检查的常用几个指标菌斑指数(PL)、牙龈指数(GI)、牙周袋探诊深度(PD)、附着丧失(AL)进行记录,用SPSS 11.0软件秩和检验分析各指标与龈沟液中CTX的相关性。结果:PL、GI、PD、AL与龈沟液中CTX浓度的Sperman秩相关系数分别为0.386(P<0.01),0.366(P<0.05),0.382(P<0.05)和0.314(P<0.05)。结论:龈沟液中CTX浓度与PL、GI、PD、AL成正相关。 Objective:To detect the correlativity between clinical periodental indexes and C-terminal telopeptides of type I collagen (CTX)concentration in gingival crevicular fluid(GCF).Methods:77 teeth with periodontitis in 60 patients from the international Bethune peace hospital were included.The concentration of CTX in GCF was detected by enzyme-linked immunosorbent assay.The plague indexe(PL),gingival indexe(GI),probing depth(PD)and attachment loss (AL)level were recorded at clinic.The correla-tion of CTX concentration and clinic indexes was analysed by Kruskal-Wallis test using SPSS 1 1 .0 software.Results:The Spearman correlation coefficient of PL,GI,PD and AL with CTX was 0.386(P 〈0.01 ),0.366(P 〈0.05),0.382(P 〈0.05)and 0.31 4(P 〈0.05)respectively.Conclusion:PL,GI,PD and AL are positively correlated with the concentration of CTX in GCF(P 〈0.05).
出处 《实用口腔医学杂志》 CAS CSCD 北大核心 2014年第2期223-226,共4页 Journal of Practical Stomatology
基金 总后勤部军队"十一五"研究(编号:06MA070)
关键词 慢性牙周炎 龈沟液(GCF) I型胶原羧基端交联肽(CTX) 酶联免疫吸附实验(ELISA) Chronic periodontitis Gingival crevicular fluid (GCF) C- terminal telopeptides of type I collagen(CTX) Enzyme- linked immunosorbent assay(ELISA)
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