摘要
目的探讨氯吡格雷联合辛伐他汀治疗不稳定型心绞痛的临床效果。方法选择本院收治的100例不稳定型心绞痛患者,随机分为观察组和对照组,每组各50例。两组均给予常规治疗,对照组给予辛伐他汀治疗,观察组给予辛伐他汀联合氯吡格雷治疗。疗程为8周,观察两组患者治疗前后白细胞介素-6和超敏C反应蛋白水平改变情况。结果观察组的白细胞介素-6、超敏C反应蛋白水平与对照组比较,差异有统计学意义,总有效率高于对照组(P<0.05)。结论氯吡格雷联合辛伐他汀能够降低不稳定型心绞痛患者白细胞介素-6和超敏C反应蛋白水平,治疗效果显著,值得借鉴。
Objective To explore the clinical effect of clopidogrel combined with simvastatin treating unstable angina pectoris. Methods 100 patients with unstable angina pectoris were selected and randomly divided into the observation group （n=50） and the control group （n=50）.The two groups were given conventional treatment,and the control group was given simvastatin while the observation group was given simvastatin combined with clopidogrel.The course was 8 weeks. The change of interleukin-6 and high sensitivity C-reactive protein level were observed before and after treatment. Results The level of interleukin-6 and high sensitivity C-reactive protein in the observation group compared with those in the control group,and there was a statistical difference of the two groups;the total effective rate of the observation group was higher than that in the control group （P〈0.05）. Conclusion Clopidogrel and simvastatin can decrease the level of interleukin -6 and high sensitivity C-reactive protein in patients with unstable angina pectoris and the treat- ment effect is significant.h is worthy of reference.
出处
《中国当代医药》
2014年第10期92-93,96,共3页
China Modern Medicine
