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碳纳米管结合药物在肿瘤靶向治疗中的应用 被引量：1

Application of functionalized carbon nanotube in tumor targeted therapy
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摘要 将药物定点运输至相关组织以提高药物利用率、降低细胞毒性的手段称为靶向治疗.以碳纳米管为载体的结合化疗药物与单纯使用药物相比,药物活性与肿瘤抑制率均有提高.碳纳米管结合免疫治疗类药物和核酸还可从免疫学和基因水平治疗肿瘤. Targeted therapy means transporting drugs to certain tissue, aiming at increasing the utiliza- tion of drugs as well as reducing cytotoxicity. Chemotherapy drugs carried by carbon nanotube have high phar- maceutical activity and tumor control rate, compared with drugs alone. Carbon nanotube combined with immu- notherapy drugs and nucleic acid can treat tumors at immunology and gene level.
作者 蒋文彬 温诗辉 赵庆华
机构地区 上海交通大学附属第一人民医院骨科 东华大学化学化工与生物工程学院
出处 《国际肿瘤学杂志》 CAS 2014年第4期258-260,共3页 Journal of International Oncology
基金 上海交通大学医工（理）交叉研究基金（YG2011MS28）
关键词 纳米管 碳 药物载体 肿瘤治疗方案 Nanotubes, carbon Drug carriers Antineoplastic protocols
分类号 R730.5 [医药卫生—肿瘤]
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参考文献16

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二级参考文献15

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共引文献5

同被引文献30

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国际肿瘤学杂志
2014年 第4期

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