摘要
目的:通过建立Wistar大鼠创伤缺损模型,检测Wistar大鼠伤口的白细胞介素-1β,观察嘎木朱尔对大鼠创伤愈合的药效.方法:将72只Wistar大鼠随机分为蒙药组,云南白药组,模型对照组和空白对照组,每组18只.除空白对照组外,其它3组Wistar大鼠均建立创伤缺损模型,蒙药组以嘎木朱尔处理、云南白药对照组以云南白药处理,模型对照组伤口不做任何处理.造模后第1、3、5、7、9、14天分批处死各组大鼠,应用酶联免疫吸附法检测大鼠伤口皮肤组织的白细胞介素-1β含量.结果:蒙药嘎木朱尔能够明显抑制创伤组织中炎症因子白细胞介素-1β,效果优于云南白药组.结论:嘎木朱尔能够促进创伤组织的再生和修复.
Objective：To investigate the efficacy of Mongolian medicine Gamuzhuer on wound healing rats through es-tablishing rat traumatic defect models and testing the interleukin-1βin rat wounded skins. Methods：72 Wistar rats were randomly divided into Mongolian medicine group, Yunnan Baiyao group, model control group and blank control group, 18 rats in each group. Except the blank control group, other groups’rats were used to establish traumatic defect models. The Mongolian medicine group was treated with Gamuzhuer, the Yunnan Baiyao group was treated with Yun-nan Baiyao, and the model control group was given nothing. After the 1, 3, 5, 7, 9, 14th days of modeling, the rats were killed and ELISA was acted to observe the interleukin-1βcontent in wound healing rats. Results：Mongolian medi-cine Gamuzhuer can inhibit interleukin-1βin wound tissue, and its efficacy was better than that of Yunnan Baiyao. Conclusion：Gamuzhuer can promote the regeneration and repairation of wounded tissues.
出处
《内蒙古民族大学学报（自然科学版）》
2014年第1期62-64,共3页
Journal of Inner Mongolia Minzu University：Natural Sciences
基金
内蒙古民族大学硕士研究生科研创新项目(S10136201302)
