摘要
目的基于文献分析探讨中医治疗癌性腹水的临床用药规律。方法检索1989年1月-2013年3月中国期刊全文数据库(CNKI)中医治疗癌性腹水相关临床文献,按中药功能、药性、药味、归经及药对进行频数和聚类分析。结果共纳入文献55篇,处方56首,中药164味、频数共668次。使用频率前6类由高到低依次为利水渗湿药、补气药、活血祛瘀药、理气药、清热解毒药、峻下逐水药,累计频率为61.83%。单药使用频数>6次的中药25味,累计频率为53.74%,前3类为利水渗湿药(5味)、补气药(4味)、活血祛瘀药(3味)。温性药使用频数最高(260次,38.92%)。药性频数共1055次,甘味药最高(354次,33.55%),其次为苦味(284次,26.92%)、辛味(268次,25.40%)。归经频数共1747次,频数>200次由高到低依次为脾经、肺经、肝经、肾经。常见药对有茯苓与白术、黄芪与桂枝等。结论治疗癌性腹水在利水渗湿基础上注重扶助正气,特别强调补气;药物性味上寒温共用,甘苦辛并重,多取脾、肺、肝、肾经药物。
Objective To summarize the herbal medication in treating malignant ascites based on literature. Methods TCM literatures concerning malignant ascites from CNKI （1989.1-2013.3） were retrieved. The herbs and those category, nature, flavor and meridian distribution were summarized by frequency method. The couple herbs were analyzed by hierarchical cluster analysis. Results Fifty-five qualified documents and 56 effective prescriptions were collected. A total of 164 herbs were used （668 frequencies）. Six groups of herbs, cumulative relative frequency （CRF） of 61.83%, were used frequently in order as follows：the herbs for promoting diuresis and resolving dampness, invigorating qi, invigorating the blood and removing blood stasis, regulating qi, eliminating heat and toxin, excreting drastically water. The most frequently used herbs （＆gt;6 frequencies, CRF 53.74%） had 25 species. The first three places were the herbs for promoting diuresis and resolving dampness （5 species）, invigorating qi （4 species）, invigorating the blood and removing blood stasis （3 species）. These herbs were mostly of warm nature （260 frequencies, 38.92%）. The total frequency of herb-nature was 1055 and the sweet （354 frequencies, 33.55%）, bitter （284 frequencies, 26.92%） and pungent （268 frequencies, 25.40%） herbs were used more frequently. The total frequency of meridian distribution was 1747 and these herbs were mostly attributed to spleen, lung, liver, and kidney meridians （＆gt;200 frequencies）. The most frequently used couple-herbs included Poria and Rhizoma Atractylodis Macrocephalae, Radix Astragali and Ramulus Cinnamomi, etc. Conclusion Invigorating qi was emphasized in treating malignant ascites, combined with promoting diuresis. The herbs of the warm and cold nature, the sweet, bitter and pungent flavor, spleen, lung, liver and kidney meridians were most frequently used.
出处
《中国中医药信息杂志》
CAS
CSCD
2014年第4期22-25,共4页
Chinese Journal of Information on Traditional Chinese Medicine
基金
上海市科委医学引导项目(12401906000)
关键词
癌性腹水
中医药疗法
文献研究
malignant ascites
TCM therapy
literature research
