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高效液相色谱法测定美托拉宗片在人体内的血药浓度

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摘要 使用反相LichroCART Purospher C 18色谱柱,流动相为乙腈和0.5%三乙醇胺(35:65)洗脱15 min。应用带有光电二极管阵列检测器的高效液相色谱仪检测美托拉宗。检测限和最低定量限分别为1 ng/ml和2.5 ng/ml。该方法成功用于美托拉宗在人血浆中的药代动力学研究,灵敏性、重现性好。
作者 孙卉玲
出处 《当代医学》 2014年第9期154-155,共2页 Contemporary Medicine
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