摘要
目的：观察甘露聚糖肽注射液治疗中重度烧伤感染的临床疗效。方法：选择2006年03月-2010年10月期间笔者所在医院收治的烧伤患者90例，随机分为对照组和治疗组，各45例，均按常规治疗，对照组患者皮下注射重组人生长激素，治疗组患者静脉注射多抗？甘露聚糖肽注射液。结果：治疗组临床有效率为93.33%较对照组显著提高（P〈0.05）。治疗组患者创面愈合率及T淋巴细胞亚群CD4＋水平和CD4＋/CD8＋比值均较对照组显著升高（P〈0.05）。两组血浆白蛋白、前白蛋白、血糖及尿钠、钾等比较差异无统计学意义（P〉0.05）。结论：中重度烧伤患者应用甘露聚糖肽注射液治疗，可增强患者机体免疫功能，促进烧伤创面愈合，提高临床疗效。
Objective：To observe the clinical efficacy of Mannatide injection in the treatment of moderate and severe burn infection. Methods：90 burn patients admitted to the hospital from March 2006 to October 2010 were randomly divided into control and treatment groups, each group had 45 cases. Both of the two groups were given conventional treatment, the control group were injected recombinant human growth hormone, the treatment group were treated with intravenous Mannatide injection.Results：The clinical effective rate of treatment group was 93.33%, which was significantly higher than the control group （P〈0.05）. The wound healing rate, CD4＋、CD4＋/CD8＋ratio in the treatment group were significantly higher than the control group （P〈0.05）. There was no statistical significance between plasma albumin, pre-albumin, glucose, and urinary sodium, urinary potassium and other indicators （P〉0.05）.Conclusion：The therapy that Mannatide injection in the treatment of patients with moderate and severe burns can enhance immune function, promote healing of burn wounds and improve clinical efficacy.
出处
《中国医药导刊》
2014年第1期143-144,共2页
Chinese Journal of Medicinal Guide
关键词
甘露聚糖肽
多抗
烧伤
重组人生长激素
Mannatide
Polyactin
Burn
Recombinant Human Growth Hormone
