摘要
目的：对肺炎克雷伯菌的临床分布及耐药情况进行探讨。方法：对来我院就诊的患者的送检标本，进行肺炎克雷伯菌的检测。对于检测出该细菌的病例，进行细菌的分离培养，然后进行常规抗生素的药敏试实验。结果：检测出的189株肺炎克雷伯菌中产ESBEs阳性的菌株有69例，占了总例数的1／3左右。该细菌在临床上的分布主要是集中在ICU、内科，急诊科三个科室。这三个科室的肺炎克雷伯菌检出例数占总检出例数的的70％以上。根据药敏实验的结果：ESBLs阳性菌株的耐药性明显高于ESBLs阴性的耐药性两者的差异具有统计学意义。结论：肺炎克雷伯菌的耐药现象在临床药敏实验的检测结果中显示，耐药率特别高，特别是产ESBLs肺炎克雷伯菌。为了有效控制耐药菌株的产生和传播。
Objective： the clinical distribution and drug resistance ofKlebsiella pneumoniaewere discussed. Methods： in our hospital for treatment of patientsamples, detection of Klebsiella pneumoniae. For thedetection of the bacterial cases, isolation and culture of bacteria, drug sensitive testandconventional antibiotics. Results： the detection of 189 strains of Klebsiella pneumoniae producing ESBLs positive strains were 69 cases, accounting for the total number of casesabout 1/3. The distribution of the bacteria in clinical practice is mainly concentrated in the ICU, Department of internal medicine, emergency department three departments. Klebsiella pneumoniae three departments the number of detected cases accounted for more than the total number of 70% positive cases. According to the drug sensitivity test results ： significant anti- biotic resistance of ESBLs producing strains was significantly higher than that of ESBLs negative resistance difference. Conclusion： the drug resistance of Klebsiella pneumoniae in clinical detection results showed the sensitivity test, drug resistance rate is particularly high, especially ESBLs producing Klebsiella pneumoniae. In order to produce and effective control of the spread of drug - resistant strains of the implementa- tion, we should strengthen the control of Klebsiella pneumoniae and clinical treatment of dru~ sensitive test.
出处
《药物与人》
2014年第01S期4-4,14,共2页
Medicine & People
关键词
肺炎克雷伯菌
临床分布
耐药性
Klebsiella pneumonia
clinical distribution
drug resistance
