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辨证分型联合西药治疗急性肾炎随机平行对照研究 被引量:4

Parallel Randomized Controlled Study of Acute Nephritis Syndrome Type Combined with Western Medicine
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摘要 [目的]观察辨证分型联合西药治疗急性肾炎疗效。[方法]使用随机平行对照方法.将60例住院患者按随机数字表法分为两组。对照组30例双氢克尿噻,1~2mg/kg,3)L/d,口服。氨苯蝶啶片1~2mg/kg+10%葡萄糖10mL,4~6次/d,静注;高血压加硝苯吡啶,0.1~0.2mg/kg,2~3次/d,口服。治疗组30例①风水相博。麻黄连翘赤小豆汤合五苓散(麻黄3~6g,连翘9g,赤小.9-30g,五苓散5g)。②阴虚邪恋,知柏地黄丸合二至丸(知母、黄柏、桑白皮、黄芩、山楂、甘草各10g,生地15g,女贞子、旱莲草各20g,丹参30g),1剂/d,水煎100mL,早晚口服。西医治疗同对照组。连续治疗15d为1疗程。观测临床症状、不良反应。连续治疗4疗程,判定疗效。[结果]治疗组痊愈22例。显效6例.有效1例.无效1例.总有效率96.67%。对照组痊愈15例.显效4例.有效1例。无效10例.总有效率66.67%。治疗组疗效优于对照组(P〈0.05)。生化指标改善治疗组优于对照组(P〈0.05)。[结论]辨证分型联合西药治疗急性肾炎效果显著.值得推广。 [ Objective ] To observe the therapeutic effect of syndrome differentiation of TCM combined with western medicine in treatment of acute glomerulonephritis. E Methods ] Using randomized controlled methods, will be divided into two groups according to the random number table, 60 cases of hospitalized patients. A control group of 30 cases of hydrochlorothiazide, 1 - 2mg/kg, 3/d, oral. Triamterene Tablets 1 - 2mg/kg + 10% glucose 10mL, 4 - 6/d, intravenous injection plus nifedipine; hypertension, 0.1 - 0.2mg/kg, 2 3/d, oral. The treatment group of 30 cases of Feng Shui with Bo, ephedra Forsythia adzuki beans soup Poria five powder (Mahuang 3 - 6g, Lianqiao 9g, Chixiaodou 30g, Wulingsan 5g ) . The Yin evil love, Zhibai Dihuang pills two pills to ( Zhimu, Huangbo, Sangbaipi, Huangqin, Shanzha, Gancao each 10g, Shengdi 15g, Nvzhenzi, Hanliancao each 20g, Danshen 30g ) . These drugs were 1 agent/d, water simmer in water 100mL, sooner or later oral. Western medicine treatment with the control group. Continuous treatment with 15d for 1 courses. Observation of clinical symptoms, adverse reaction. Continuous 4 courses of treatment, the curative effect. [ Results ] The treatment group cured 22 cases, effective in 6 cases, effective 1 cases, invalid 1 eases, the total efficiency of 96.67%. The control group 15 cases were cured, 4 cases markedly effective, effective 1 cases, invalid 10 cases, the total efficiency of 66.67%. The treatment group was better than control group ( P〈 0.05 ) . Biochemical index were improved in treatment group than in control group ( P〈 0.05 ) . [ Conclusion ] Syndrome differentiation treatment of traditional Chinese medicine combined with western medicine in the treatment of acute nephritis effect is significant, worthy of promotion.
作者 张观刚
出处 《实用中医内科杂志》 2014年第1期102-104,共3页 Journal of Practical Traditional Chinese Internal Medicine
关键词 急性肾炎 麻黄连翘赤小豆汤 五苓散 知柏地黄丸 二至丸 双氢克尿噻 氨苯蝶啶片 硝苯吡啶 随机平行对照研究 Acute nephritis Mahuang Lianqiao Chixiaodou soup Wulingsan ZDP Erzhiwan Hydrochlorothiazide Triamterene tablets nifedipine Randomized parallel group study
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