摘要
目的探讨尿微量白蛋白测定在糖尿病肾病早期诊断中的价值及其影响因素。方法以放射免疫分析法对79例2型糖尿病患者尿微量白蛋白进行测定,同时采用常规生化检查方法检测血肌酐、尿酸、血糖及糖化血红蛋白等指标,并详细记录相关的临床资料。分析尿微量白蛋白与血生化指标以及相关临床指征变化的关系。结果尿微量白蛋白在血生化指标改变之前即已出现,其含量的增加伴随着肾功能的恶化。高尿酸血症、血糖控制不良等因素可加剧糖尿病肾损害的发生。结论微量白蛋白尿是糖尿病肾病发生的早期信号,其发生发展受到多种因素的影响。
Objective To explore the value of elevated urinary microalbumin in patients with type 2 diabetes melli- tus （T2DM） and the influential factors. Methods Urinary microalbumin of 79 T2DM patients were detected. The associ- ation of urinary microalbumin with serum creatinine （Scr）, hyperuricemia and clinical signs were analysed. Results Elevated urinary microalbumin occurred before the increasing of Scr, and its increase was eompanied with the deterioration of the kidney function. Hyperuricemia, hypertension and uncontrolled blood glucose could worsen the kidney function. Con- elusion Urinary microalbumin is a sensitive markers for early renal function damage in T2DM patients whose occurrence and development is affected by multiple factors.
出处
《华南国防医学杂志》
CAS
2014年第2期110-112,共3页
Military Medical Journal of South China
关键词
2型糖尿病
尿白蛋白
危险因子
Type 2 diabetic mellitus
Urinary microalbumin
Risk factors
