摘要
Hepatitis C vires(HCV)constitutes a significant health burden worldwide,with an estimated 130-170 million people chronically infected.Severe liver disease,including advanced fibrosis,cirrhosis and hepatocellular carcinoma,is often a complication of long term infection,making HCV the most common in-
Hepatitis C virus （HCV） constitutes a significant health burden worldwide,with an estimated 130-170 million people chronically infected.Severe liver disease,including advanced fibrosis,cirrhosis and hepatocellular carcinoma,is often a complication of long term infection,making HCV the most common indication for liver transplantation in developed countries （Thomas D L,2013）.Besides liver disease,persons with chronic HCV infection also have a high prevalence of multiple extrahepatic conditions compared to agematched,general population controls.
基金
supported by theDFG through SFB TRR60
