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小儿川崎病冠状动脉病变的临床探究 被引量:2

Clinical investigation of coronary artery disease in children with Kawasaki disease
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摘要 目的探讨小儿川崎病冠状动脉病变的临床治疗方法与治疗效果。方法选取2003年6月~2013年6月来我院接受治疗的川崎病冠状动脉病变患儿30例,采用超声心动图对这些患者冠状动脉受伤的情况进行检查,并采用Cubens的方式测定患儿左心室收缩功能的情况,采用二尖瓣多普勒血流图测定这些患者的左心室舒张功能,同时与30例正常儿童的心功能状况进行对比分析。结果在30例冠状动脉受到损伤的患儿中,有21例患儿的冠状动脉扩张情况在治疗4个月的时间内得到了控制并逐渐好转,有8例患儿的冠状动脉扩张情况在治疗6个月时间内逐渐得到好转,只有1例患儿在6个月的随访调查中发现其病情并未出现好转。结论川崎病患儿在发病时冠状动脉很容易受到影响,尤其出现在急性期,而对心功能的改变影响则不明显,临床诊断中应用超声心动图诊断效果显著,值得广泛推广和应用。 Objective To investigate the clinical treatment and outcome of coronary artery disease in children with Kawasaki disease (KD). Methods Thirty KD children with coronary artery disease receiving treatment in our hospital from June 2003 to June 2013 were included in the study. Eehocardiography was used to examine the coronary artery in these patients. The left ventricular systolic function of these patients was evaluated (Cubens), and the left ventricular diastolic function was evaluated by color Doppler flow imaging of the mitral valve. These patients were compared with 30 healthy children in terms of cardiac traction. Results Among 30 patients, 21 showed controlled and reduced coronary artery ectasia within 4 months of treatment, 8 showed reduced coronary artery ectasia within 6 months of treatment, and only one showed no improvement in 6 months of follow-up. Conclusion The coronary artery tends to be affected in children with KD, especially during the acute stage, but there is no significant change in cardiac function. Echocardiography has a significant diagnostic value for coronary artery disease in children with KD and holds promise for clinical application.
作者 陆春云
出处 《心血管病防治知识(学术版)》 2014年第3期62-64,共3页 Prevention and Treatment of Cardiovascular Disease
关键词 小儿川崎病冠状动脉病变 临床探究 Coronary artery disease in children with Kawasaki disease Clinical investigation
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