摘要
目的对胸腔镜下和传统开胸手术对中国人群早期肺癌患者疗效的比较采用Meta分析,为胸腔镜的临床应用提供循证学依据。方法检索"万方数据库"(WANFANGDATA)和"中国知网数据库"(CNKI),查找关于胸腔镜和开胸手术治疗早期肺癌的对照研究,采用Rev Man 4.2对数据进行汇总分析。结果共纳入11项研究。Meta分析显示2组手术时间差异无统计学意义(Z=0.98,P=0.33),但淋巴结清扫组数(Z=2.07,P=0.04)、引流时间(Z=24.82,P<0.01)、术中出血量(Z=70.67,P<0.01)、住院时间(Z=19.90,P<0.01)和并发症发生率(Z=1.92,P=0.05)差异均有统计学意义。结论现有临床资料证实对早期肺癌采用胸腔镜下手术,其淋巴结清扫更为彻底,并且术后并发症少、创伤小、术后恢复快。
Objective To compare the efficacy of video-assisted thoraeoscopic surgery and traditional open thoracotomy on Chinese people with early-stage lung cancer by a Meta-analysis, in order to provide the evidence-based medicine basis for the clinical application of thoracoscopic surgery. Methods We searched the randomized controlled trials about the thora- coscopic surgery and traditional open thoracotomy for the early-stage lung cancer from in WanFang Database and CNKI, and the gathered data were analyzed by Rev Man 4.2. Results A total 11 randomized controlled trials were included. Meta-analysis showed that the operation time was similar in the two groups （ Z = 0.98, P = 0.33 ）, but the number of lymph nodes resected （Z = 2.07, P = 0.04）, duration of drainage （ Z = 24.82, P 〈 0. 01 ）, intraoperative blood loss （ Z = 70.67, P 〈 0.01 ）, length of hospital stay （ Z = 19.90, P 〈 0.01 ） and incidence of complication （ Z = 1.92, P = 0.05 ） all gave significant differences. Conclusion The thoracoscopic surgery in the treatment for early-stage lung cancer can resect the lymph node thoroughly ,with the advantage of less postoperative complications, small trauma, and quick recovery.
出处
《中华全科医学》
2014年第4期607-609,共3页
Chinese Journal of General Practice
关键词
META分析
电视辅助胸腔镜手术
肺癌
并发症
Meta-analysis
Video-assisted thoracoscopic surgery
Lung cancer
Complications
