摘要
目的：通过检测儿童唾液和菌斑中高相对分子质量唾液粘蛋白（MGI）含量,探讨其与乳牙患龋状况之间的关系,为临床治疗乳牙龋病治疗提供依据.方法：依据世界卫生组织（WHO）《口腔健康调查的基本方法）》,选取无龋组（DMFT=0）、低龋组（1＜DMFT＜4）、高龋组（DMFT＞5） 3～5岁幼儿各20名,采用吐出法收集幼儿4mL左右非刺激性唾液,采用酶联免疫法测定MGI含量并进行统计分析.结果：无龋组、低龋组、高龋组唾液中MGI含量依次降低,无龋组与低龋组以及低龋组与高龋组间,唾液中MGI含量无统计学差异（P＞0.05）,无龋组与高龋组间,唾液中MGI含量有统计学差异（P＜0.05）;无龋组、低龋组、高龋组唾液中MGI含量均无性别差异,差异无统计学意义（P＞0.05）.结论：随着龋病的发生和发展,幼儿唾液中的MGI含量逐渐降低,且MG]含量无性别差异,这表明MGI具有一定的抗龋活性.
Objective Analysis the high-molecular-weight salivary mucin （MGI） content and the relationship between caries status of children,in order to provide the basis for salivary mucin research.Methods By roughly the same number of age and gender randomly selected the three groups （no caries group：DMFT=0;low caries group：1 ≤DMFT≤4;high caries group：DMFT＞5） of 20children by ＂The basic method of oral health survey＂ which formulated by WHO.Then took these children＇s plaque and saliva,analysis the MGI content by ELISA kit,and the results were statistically analyzed.Results The content of MGI in no caries group,low caries group,high caries group descended in order.There were no significant difference between no caries group and low caries group （P＞0.05）,also the low caries group and high caries group （P＞0.05）.There were significant difference no caries group and high caries group （P＜0.05）.There were no significant difference in the content of MGI between boy and girl （P＞0.05）.Conclusion The content of MGI descended as happen and development of the caries.MG1 concentration in saliva of children showed no significant correlation by gender.
出处
《中国美容医学》
CAS
2014年第4期322-324,共3页
Chinese Journal of Aesthetic Medicine
关键词
高分子量唾液粘蛋白
乳牙患龋
相关性分析
high-molecular-weight salivary mucin
primary caries status
correlation analysis
