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保留脾脏的胰体尾切除术的临床研究 被引量:1

Clinical research of spleen-preserving distal pancreatectomy
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摘要 目的 探讨保留脾脏的胰体尾切除术的安全性、可行性及应用价值.方法 回顾性分析2009年10月至2013年6月因胰体尾良性及低度恶性肿瘤行胰体尾切除术38例患者的临床资料,根据手术方式分为保留脾脏胰体尾切除术组(SPDP组,18例)和联合脾脏切除术组(DPS组,20例).比较两组手术时间、术中出血量、围术期血小板计数、术后住院观察时间、并发症发生率及死亡情况.结果 SPDP组与DPS组相比,术后第3天及第7天血小板计数较低且基本在正常范围内[第3天(187.8±50.4)×10^9/L与(253.9±54.5)×10^9/L,第7天(202.7±48.0)×10^9/L与(356.4±63.4)×10^9/L],差异均有统计学意义(P〈0.01);住院观察时间短[(11.6±2.2) d与(14.1±2.3) d],差异有统计学意义(P〈0.01).手术时间[(188.6±20.1) min与(180.8±29.8) min]、术中出血量[(212.2±120.9) ml与(224.0±113.3) ml]、术后并发症发生率(16.7%与30.0%)等比较,差异均无统计学意义(P〈0.05).结论 对于胰体尾部良性及低度恶性肿瘤保留脾脏的胰体尾切除术是安全、可行的,且可降低深静脉血栓形成的风险. Objective To explore the security, feasibility and value of spleen-preserving distal pancreatectomy (SPDP). Methods The clinical data of 38 patients with benign or low-grade malig- nant pancreatic tumor undergoing distal pancreatectomy(SPDP, n = 18; DPS, n = 20)during October 2009 to June 2013 were analyzed. Such parameters as operative duration, intraoperative blood loss vol ume, perioperative platelet counts, postoperative observation time, complications and death were corn pared. Results Compared with the DPS group, the SPDP group had a lower level of platelets [ (187. 8 ± 50. 4) ×10^9/L vs. (253. 9 ± 54. 5) ×10^9/L at Day 3 and (202. 7 ± 48. 0) ×10^9/L vs. (356. 4 ± 63. 4) ×10^9/L at Day 7] and shorter postoperative time [(11.6 ± 2. 2)vs. (14. 1 ± 2. 3)days] . All differ- ences had statistical significance (P〈0. 01). No significant inter-group differences existed in operative duration [(188. 6 ± 20. 1 ) vs. (180. 8 ± 29. 8)min], blood loss volume [(212. 2 ± 120. 9) vs. (224. 0 ±113.3) roll or incidence of complications(16. 7% vs. 30. 0%)(P〈0. 05). Conclusions SPDP is both safe and feasible for benign or low-grade malignant pancreatic tumors. And it may reduce the risks of deep venous thrombosis.
出处 《腹部外科》 2014年第1期34-37,共4页 Journal of Abdominal Surgery
关键词 胰腺肿瘤 胰腺切除术 保留脾脏 Pancreatic neoplasms Pancreatectomy Spleen-preserving
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