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氯雷他定联合布地奈德治疗小儿支气管哮喘合并变应性鼻炎临床分析 被引量:6

Clinical analysis of loratadine combined with budesonide in treating bronchial asthma complicated with allergic rhinitis in children
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摘要 目的:观察氯雷他定联合布地奈德对支气管哮喘合并变应性鼻炎的临床疗效。方法:将94例支气管哮喘合并变应性鼻炎患儿随机分为观察组和对照组,每组各47例,两组患儿均采用对症治疗,观察组在此基础上给予氯雷他定,同时雾化吸入布地奈德气雾剂,治疗周期均为2周,记录并比较两组患儿治疗前后鼻炎症状评分及哮喘症状评分。结果:治疗前,两组患儿哮喘症状评分及鼻炎症状评分相近,差异不显著(P>0.05);治疗结束后,两组患儿哮喘症状评分及鼻炎症状评分均有不同程度的降低,观察组患儿症状评分值下降尤为显著,与治疗前及治疗后同期对照组比较,差异均具有统计学意义(P<0.05)。结论:氯雷他定联合布地奈德治疗小儿支气管哮喘合并变应性鼻炎的临床疗效显著,可显著降低患者症状评分。 Objective To .bserve the clinical efficacy of loratadine and budesonide in treating bronchial asthma complicated with allergic rhinitis in children. Method 94 cases were randomly divided into observation group and control group ,47 eases in each group. the children in two group were given symptomatic treatment. On the basis of this,the children in the observation group were given loratadine and budesonide for 2 weeks,the rhinitis symptom score and asthma symptom score were compared between the two groups before and after treat- ment. Resulls Before treatment,the rhinitis symptom score and asthma symptom score of the children in two groups were similar, the differenee was not slgniflcant (P 〉 0.05 ) ;After treatment,the symptom scores in the observation group were significantly lower than those in the control group ( P 〈 0.05 ). Conclusion The conjoint thearapy of desloratadine combined with budesonide has excellent treatment effect in treating bronchial asthma complicated with allergic rhinitis in children, can significantly decrease the symptom scores.
出处 《吉林医学》 CAS 2014年第7期1378-1379,共2页 Jilin Medical Journal
关键词 氯雷他定 布地奈德 变应性鼻炎 支气管哮喘 Loratadine Budesonide Allergic rhinitis Bronchial asthma
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